DRX Series

Fully automated switchSENSE® instruments are 96 well plates compatible and manufactured in Germany.

Wide ranging, deep data content on molecular interactions.
Binding Kinetics & Affinity I Protein Diameter

Conformational Change I Enzymatic Activity I Bispecific Binders & Avidity I Melting & Thermodynamics I Multimers & Aggregation

DRX Series

The DRX and DRX2 analyzers combine liquid handling, chip management and data capture for switchSENSE®measurements. Bespoke electronics manage the electrical actuation of biomolecules on the biochip and measurement of molecular dynamics via time-correlated single photon counting. The instrument also offers the proprietary electrical desorption methodology to adjust capture molecule densities.

Instruments are designed for walk-away operation with automated dilution series / liquid handling, temperature managed environments and stability for long overnight / multi-day studies.

Limit of detection 10 fM
Dissociation constant 50 fM – 1 mM
Association rate constant 1E3 – 1E8 /Ms
Dissociation rate constant 1E-6 – 1E0 /s
Hydrodynamic diameter accuracy of 0.1 nm
Temperature 8° – 75°C (chip), 10° – 40°C (autosampler)

Introducing the DRX2

The double color DRX2 analyzer offers the simultaneous measurement of two different species of probes on the same biochip electrode.

Each sensor spot carries two nanolever sequences, one with a red tag, and one with a green. The instrument tracks the movement and position of the different nanolevers separately and simultaneously.

This technology offers novel methods of investigation including same-spot controls, dual binding modelling, ideal for bispecifics and Proof of Action experiments with two nanolevers to play with, using one nanolever for capture and the second for detection.

Have a look at our DRX2 Flyer

Limit of detection 10 fM
Dissociation constant 50 fM – 1 mM
Association rate constant 1E3 – 1E8 /Ms
Dissociation rate constant 1E-6 – 1E0 /s
Hydrodynamic diameter accuracy of 0.1 nm
Temperature 8° – 75°C (chip), 10° – 40°C (autosampler)