Consumables

Conjugation kits, buffers & more

Biochips

Demo & IQ / OQ Kits

Coupling Kits

Consumables (General), Buffers & Solutions

Overview of Biochips

Multi-purpose Chips

Multi-purpose chips are versatile means to analyze protein-protein, protein-small molecule, DNA/RNA-protein, and DNA/RNA-small molecule interactions.

By exchanging the standard complementary DNA strand, the chip design enables users to build a near infinite range of molecular structures.

Choose from two different nanolevers: standard DNA levers comprise 48 bp and are 16 nm long, or use 96 bp (32 nm) levers for large analytes.

Multi-purpose chips are available in two quality grades: Standard Grade and Performance Grade

Email order@dynamic-biosensors.com for ordering and product information.

Order No.Product description
MPC-48-1-R1-SNanolevers with 48 bases; 6 single sequence spots (B); red fluorophore; performance grade; suitable for DRXred and DRX2
MPC-48-1-Y1-SNanolevers with 48 bases; 6 single sequence spots (B); yellow fluorophore; standard grade; suitable for DRXyellow
MPC-96-1-R1-SNanolevers with 96 bases; 6 single sequence spots (B); red fluorophore; standard grade; suitable for DRXred and DRX2
MPC-96-1-Y1-SNanolevers with 96 bases; 6 single sequence spots (B); yellow fluorophore; standard grade; suitable for DRXyellow
MPC-48-2-R1-SNanolevers with 48 bases; 2 reference sequence spots (A) and 4 probe sequence spots (B); red fluorophore; standard grade; suitable for DRXred and DRX2
MPC-48-2-Y1-SNanolevers with 48 bases; 2 reference sequence spots (A) and 4 probe sequence spots (B); yellow fluorophore; standard grade; suitable for DRXyellow
MPC-96-2-R1-SNanolevers with 96 bases; 2 reference sequence spots (A) and 4 probe sequence spots (B); red fluorophore; standard grade; suitable for DRXred and DRX2
MPC-96-2-Y1-SNanolevers with 96 bases; 2 reference sequence spots (A) and 4 probe sequence spots (B); yellow fluorophore; standard grade; suitable for DRXyellow
MPC2-48-2-G1R1-SNanolevers with 48 bases; 6 double-sequence spots (A,B) for on-spot referencing or double probe measurements; green and red fluorophores; standard grade; suitable for DRXred and DRX2
MPC2-96-2-G1R1-SNanolevers with 96 bases; 6 double-sequence spots (A,B) for on-spot referencing or double probe measurements; green and red fluorophores; standard grade; suitable for DRXred and DRX2
MP3-96-2-G1R1-SMP3 Multi-Purpose Biochip with 3 different nanolever densities

Nanolevers with 96 bases; 6 double-sequence spots (A,B) for on-spot referencing or double probe measurements; green and red fluorophores; standard grade; suitable for DRXred and DRX2

With its three predefined ligand surface densities, the chip makes it easy to experiment with different and ultra-low densities, and ensures quick experimental success even for challenging interactants.

Bi-functional Chips

Traditional methods used in the study of bi-functional antibodies can often fail to discriminate between complex binding modes (monovalent versus bivalent or bispecific). The new switchSENSE® Bi-functional Chips offer a very flexible and powerful platform for both research and quality control in production.

Multiple binding events can be studied either through the use of bi-functional nanolevers that present two different ligands at the same time or through a heterogeneous design where two nanolevers species are immobilized in direct proximity.

Email order@dynamic-biosensors.com for ordering and product information.

Order No.Product description
BIF-96-2-R1-SBi-functional Biochip for two antigens (distance 7 nm or 14 nm); nanolevers with 96 bases; 2 reference sequence spots (A) and 4 probe sequence spots (B); red fluorophore; standard grade; suitable for DRXred and DRX2
BIF-96-2-Y1-SBi-functional Biochip for two antigens (distance 7 nm or 14 nm); nanolevers with 96 bases; 2 reference sequence spots (A) and 4 probe sequence spots (B); yellow fluorophore; standard grade; suitable for DRXyellow
BIF2-96-2-G1R1-SBi-functional Biochip for two antigens (distance 7 nm or 14 nm); nanolevers with 96 bases; 6 double-sequence spots (A,B) for on-spot referencing or double probe measurements; green and red fluorophores; standard grade; suitable for DRXred and DRX2

Enzyme Chips

Our unique enzyme chips are designed to analyze the activity of polymerases and nucleases. Elongation rates, exo- or endonuclease activity, hot start properties, and many other parameters can be analyzed cost efficient and non-hazardous in fully automated, radiation free, and rapid protocols.

Label-free polymerase assays are ready-to-use. The nanolever structure consists of a double stranded primer part and a single stranded template. Two versions with different lengths are available: P36T54 and P36T80. The kit includes unlabeled complementary DNA.

Email order@dynamic-biosensors.com for ordering and product information.

Order No.Product description
ENZ-80-1-R1-SNanolevers with 80 bases; 6 single sequence spots (B); red fluorophore; standard grade; suitable for DRXred and DRX2
ENZ-80-1-Y1-SNanolevers with 80 bases; 6 single sequence spots (B); yellow fluorophore; standard grade; suitable for DRXyellow

Performance verified Chips

 

Performance verified chips for use in QC and GxP environments
All biochips are available as performance verified versions upon request. Performance verified chips are especially selected and each detection spot is extensively tested under application conditions and QC approved. Comprehensive QC documentation of performance indicators is provided with every chip for consistent traceability of results.
Recommended for use in QC or GxP environments.
Please contact order@dynamic-biosensors.com for details.

Cleaning Chip

 

G-01-1
Chip for cleaning purposes with microfluids, without DNA.

Custom-made Chips

 

Custom biochips with tailor-made surface modifications are available upon request. Please contact order@dynamic-biosensors.com and describe your application. A chip specialist will get in touch with you shortly to discuss technical requirements, solutions, and provide you with timeline and cost estimates.

Coupling Kits

To link a ligand onto the complementary DNA strand, we offer a range of Coupling Kits. For further information about the binding theory and chip functionalization please check our Application Library. In case you have any questions, please contact info@dynamic-biosensors.com.

Email order@dynamic-biosensors.com for ordering and product information.

Order No.Product Description
CK-NH2-1-B48Amine coupling kit 1 for 48 mer
for proteins (>5 kDa); cNL-B48 and NHS modifier, sufficient for 5 different conjugations
CK-NH2-1-A48Amine coupling kit 1 for 48 mer for double color applications
for proteins (>5 kDa); cNL-A48 and NHS modifier, sufficient for 5 different conjugations
CK-NH2-1-B96Amine coupling kit 1 for 96 mer
for proteins (>5 kDa); cNL-B96 and NHS modifier, sufficient for 5 different conjugations
CK-NH2-1-A96Amine coupling kit 1 for 96 mer for double color applications
for proteins (>5 kDa); cNL-A96 and NHS modifier, sufficient for 5 different conjugations
CK-NH2-2-B48Amine coupling kit 2 for 48 mer
for proteins (>5 kDa); cNL-B48 and NHS modifier, sufficient for 5 different conjugations (spin column purification)
CK-NH2-2-B96Amine coupling kit 2 for 96 mer
for proteins (>5 kDa); cNL-B96 and NHS modifier, sufficient for 5 different conjugations (spin column purification)
CK-NH2-3-B48Amine coupling kit 3 for 48 mer
for small molecules and peptides (< 5 kDa); cNL-B48 and NHS modifier, sufficient for 5 different conjugations
CK-NH2-4-B48Amine coupling kit 4 Micro for 48 mer
for proteins (> 5 kDa); cNL-B48 and NHS modifier, sufficient for 5 different conjugations, uses low amount of ligand (for testing purpose)
CK-NH2-5-B96Amine coupling kit 5 for 96 mer
for bi-functional analytes; two antigens (distance 7 nm) - one nanolever NHS modifier, sufficient for 5 different conjugations
CK-NH2-6-B96Amine coupling kit 6 for 96 mer
for bi-functional analytes; two antigens (distance 14 nm) - one nanolever NHS modifier, sufficient for 5 different conjugations
CK-NH2-7-B48Amine coupling kit 7 for 48 mer
for proteins (> 5 kDa) with a low pI (pI < 6); cNL-B48 and NHS modifier, sufficient for 5 different conjugations
CK-NH2-7-B96Amine coupling kit 7 for 96 mer
for proteins (> 5 kDa) with a low pI (pI < 6); cNL-B96 and NHS modifier, sufficient for 5 different conjugations
CK-SH-1-B48Thiol coupling kit 1 for 48 mer
for proteins (>5 kDa); cNL-B48 and Maleimide modifier, sufficient for 5 different conjugations
CK-SH-1-B96Thiol coupling kit 1 for 96 mer
for proteins (>5 kDa); cNL-B96 and Maleimide modifier, sufficient for 5 different conjugations
CK-SH-2-B48Thiol coupling kit 2 for 48 mer
for proteins (>5 kDa); cNL-B48 and Maleimide modifier, sufficient for 5 different conjugations (spin column purification)
CK-SH-2-B96Thiol coupling kit 2 for 96 mer
for proteins (>5 kDa); cNL-B96 and Maleimide modifier, sufficient for 5 different conjugations (spin column purification)
CK-SH-3-B48Thiol coupling kit 3 for 48 mer
for small molecules and peptides (< 5 kDa); cNL-B48 and Maleimide modifier, sufficient for 5 different conjugations
CK-CLK-1-B48Click coupling kit for 48 mer
cNL-B48 with DBCO modification, sufficient for 5 different reactions
CK-BI-1-B48Biotin kit for 48 mer
cNL-B48 modified with Biotin, sufficient for 20 regenerations
CK-BI-1-B96Biotin kit for 96 mer
cNL-B96 modified with Biotin, sufficient for 20 regenerations
CK-DG-1-B48Digoxigenin kit for 48 mer
cNL-B48 modified with digoxigenin, sufficient for 20 regenerations
CK-DG-1-B96Digoxigenin kit for 96 mer
cNL-B96 modified with digoxigenin, sufficient for 20 regenerations
CK-TN-1-B48Tris-NTA kit for 48 mer
cNL-B48 modified with Tris-NTA, sufficient for 20 regenerations
CK-TN-1-B96Tris-NTA kit for 96 mer
cNL-B96 modified with Tris-NTA, sufficient for 20 regenerations
CK-SA-1-B48Streptavidin kit for 48 mer
cNL-B48 modified with Streptavidin, sufficient for 20 regenerations
CK-SA-1-B96Streptavidin kit for 96 mer
cNL-B96 modified with Streptavidin, sufficient for 20 regenerations
CK-SXT-1-B96Strep-Tactin® XT for 96 mer
cNL-B96 modified with Strep-Tactin®XT*, sufficient for 20 regenerations
CK-FC-1-B48Fc binding Protein A kit for 48 mer
cNL-B48 modified with Protein A, sufficient for 20 regenerations
CK-FC-1-B96Fc binding Protein A kit for 96 mer
cNL-B96 modified with Protein A, sufficient for 20 regenerations
CK-FC-2-B48Fc binding Protein G kit for 48 mer
cNL-B48 modified with Protein G, sufficient for 20 regenerations
CK-FC-2-B96Fc binding Protein G kit for 96 mer
cNL-B96 modified with Protein G, sufficient for 20 regenerations
CK-GFP-1-B48GFP binding protein kit for 48 mer
cNL-B48 modified with GFP binding protein**, sufficient for 20 regenerations
CK-GFP-1-B96GFP binding protein kit for 96 mer
cNL-B96 modified with GFP binding protein**, sufficient for 20 regenerations
CK-GST-1-B48GST binding protein kit for 48 mer
cNL-B48 modified with GST binding protein**, sufficient for 20 regenerations
CK-GST-1-B96GST binding protein kit for 96 mer
cNL-B96 modified with GST binding protein**, sufficient for 20 regenerations
RK-PA-1Reducing Agent Kit 1 for Proteins and Antibodies
Chemical Reduction of disulfide bonds with TCEP

*Strep-Tactin®XT is a product of IBA Lifesciences

 

 

**GFP / GST binding protein is a product of ChromoTek GmbH

Demo & IQ / OQ Kits

Demo Kits are ideal for teaching or revision. Supplied with a detailed user’s manual and reagents they will guide users through a full experiment. For internal operation qualification, we offer an OQ Kit.

In general we recommend an annual service visit, which includes a complete documented re-qualification of the instrument according to QC standards.

Email order@dynamic-biosensors.com for ordering and product information.

Order No.Product Description
DK-AP-1-B48Demo kit protein – protein (DH |kon | koff)
Sizing of carbonic anhydrase, association of an antibody, needs Multi-purpose Biochips with NL-B48 or Customized Biochips
DK-DC-1-B48Demo kit protein – small moleucule – Dual color (kon | koff)
Association and dissociation of two antibody fabs in parallel
DK-DP-1-T80Demo kit DNA – protein (kon | kcat | koff)
Association, elongation and dissociation of a DNA polymerase, needs Enzyme Biochips with NL-T80 or Customized Biochips
DK-SP-1-B48Demo kit protein – small molecule (kon | DH | koff)
Association, size and dissociation of an anti-DIG Fab fragment, needs Multi-purpose Biochips with NL-B48 or Customized Biochips
DK-TM-1-B48Demo kit thermal melting (TM)
Thermal melting of double-stranded DNA, needs Multi-purpose Biochips with NL-B48 or Customized Biochips
IQ-KST-1-B48IQ kit
For internal operation qualification processes on customer site.
OQ-KST-1-B48OQ kit
For internal operation qualification processes on customer site. Comes with a detailed protocol to check the instrument for temperature stability, kinetics and sizing

Consumables (General)

All the necessary glassware, vials, well plates and other consumables you may need for your switchSENSE® studies.

Email order@dynamic-biosensors.com for ordering and product information.

Order No.Product description
AV-015-100NAutosampler vials 1.3 mL (glass)
1.3 mL autosampler vials and caps, 100 pcs.
AV-100-100Autosampler vials 10 mL (glass)
10 mL autosampler vials and caps, 100 pcs.
AV-T-015-100Autosampler vials 1.5 mL (glass)
1.5 mL autosampler vials (low dead volumne: <2 µl) and caps, 100 pcs.
BC-250-1Buffer bottle cap
Cap with connectors for 250 mL buffer bottle (glass) with GL 45 thread
BC-500-1Waste bottle cap
Cap with hole for 500 mL waste bottle (glass) with GL 45 thread
BO-250-1Buffer bottle 250 mL
250 mL buffer bottle (glass) with GL 45 thread
BO-500-1Waste bottle 500 mL
500 mL waste bottle (glass) with GL 45 thread
CF-003-5Centrifugal filter unit 3 kDa
Centrifugal filter unit (3 kDa MWCO), 5 pcs.
CF-010-5Centrifugal filter unit 10 kDa
Centrifugal filter unit (10 kDa MWCO), 5 pcs.
G-01-1Cleaning Chip
Chip for cleaning purposes with microfluidics, without DNA
SY-250-1Injection syringe
250 μL injection syringe for usage with automated purifier system
TB-CC-1-1Chromatographic column
Chromatographic column for usage with automated purifier system
VR-013-50-1Autosampler vial rack
Rack for 50 x 1.3 mL autosampler vials (AV-015-100N).
WP-096-150-596 well plate 150 μL
96 well plate with 150 μL well size, for usage with 96-well plate kit, 5 pcs.
WP-SEAL-5
Sealing for 96 well plate
Fits WP-096-150-5, 5 pcs.

Buffers & Solutions

We offer a range of standard buffers and solutions optimized for switchSENSE® experiments.

The platform is highly tolerant to a wide range of buffers. Download our compatibility chart at our Application Library.

Email order@dynamic-biosensors.com for ordering and product information.

Order No.Product description
BU-TE-40-1010x Buffer TE40 pH 7.4
50 mL of: 100 mM Tris-HCl, 400 mM NaCl, 0.5 % Tween20, 0.5 mM EDTA,0.5 mM EGTA;
Yields 0.5 L of: 10 mM Tris-HCl, 40 mM NaCl, 0.05 % Tween20, 50 μM EDTA,50 μM EGTA
BU-PE-40-1010x Buffer PE40 pH 7.4
50 mL of: 100 mM Na2HPO4/NaH2PO4, 400 mM NaCl, 0.5 % Tween20, 0.5 mM EDTA, 0.5 mM EGTA;
Yields 0.5 L of: 10 mM Na2HPO4/NaH2PO4, 40 mM NaCl, 0.05 % Tween20, 50 µM EDTA, 50 µM EGTA
BU-HE-40-1010x Buffer HE40 pH 7.4
50 mL of: 100 mM Hepes, 400 mM NaCl, 0.5 % Tween20, 0.5 mM EDTA, 0.5 mM EGTA;
Yields 0.5 L of: 10 mM Hepes, 40 mM NaCl, 0.05 % Tween20, 50 µM EDTA, 50 µM EGTA
BU-TE-140-1010x Buffer TE140 pH 7.4
50 mL of: 100 mM Tris-HCl, 1.4 M NaCl, 0.5 % Tween20, 0.5 mM EDTA, 0.5 mM EGTA;
Yields 0.5 L of: 10 mM Tris-HCl, 140 mM NaCl, 0.05 % Tween20, 50 µM EDTA, 50 µM EGTA
BU-PE-140-1010x Buffer PE140 pH 7.4
50 mL of: 100 mM Na2HPO4/NaH2PO4, 1.4 M NaCl, 0.5 % Tween20, 0.5 mM EDTA, 0.5 mM EGTA;
Yields 0.5 L of: 10 mM Na2HPO4/NaH2PO4, 140 mM NaCl, 0.05 % Tween20, 50 µM EDTA, 50 µM EGTA
BU-HE-140-1010x Buffer HE140 pH 7.4
50 mL of: 100 mM Hepes, 1.4 M NaCl, 0.5 % Tween20, 0.5 mM EDTA. 0.5 mM EGTA;
Yields 0.5 L of: 10 mM Hepes, 140 mM NaCl, 0.05 % Tween20, 50 µM EDTA, 50 µM EGTA
BU-C-150-11x Buffer C pH 8.0
50 mL of: 50 mM Na2HPO4/NaH2PO4, 150 mM NaCl
BU-P-150-1010x Buffer A pH 7.2
50 mL of: 500 mM Na2HPO4/NaH2PO4, 1.5 M NaCl;
Yields 0.5 L of: 50 mM NaH2PO4/NaH2PO4, 150 mM NaCl
BU-P-1000-55x Buffer B pH 7.2
50 mL of: 250 mM Na2HPO4/NaH2PO4, 5 M NaCl;
Yields 0.25 L of: 50 mM NaH2PO4/NaH2PO4, 1 M NaCl
BU-P-5-1010x P5 Buffer pH 7.3
50 mL of: 50 mM NaH2PO4/Na2HPO4 pH 7.3;
Yields 0.5 L of: 5 mM NaH2PO4/Na2HPO4 pH 7.3
BU-M-150-11x Buffer MES pH 6.5
12 mL of: 50 mM 2-(N-Morpholino)ethanesulfonic acid, 150 mM NaCl)
CNL-A48-500cNL-A48 solution
solution of complementary DNA lever for sequence A48, cNL-A48 500 μL / 1 μM
CNL-A96-500cNL-A96 solution
solution of complementary DNA lever for sequence A96, cNL-A96 500 μL / 1 μM
CNL-B48-500cNL-B48 solution
solution of complementary DNA lever for sequence B48, cNL-B48 500 μL / 1 μM
CNL-B96-500cNL-B96 solution
solution of complementary DNA lever for sequence B96, cNL-B96 500 μL / 1 μM
CNL-DP36-500Solution of dideoxy-P36 DNA
solution of Dideoxy-P36 DNA for usage with ENZ-80-1-R1-X or ENZ-80-1-Y1-X, DDO-P36 500 μL / 1 μM
CNL-P36T80-500P36T80 solution
solution of P36T80 DNA strand for usage with ENZ-80-1-R1-X or ENZ-80-1-Y1-X, P36T80 500 μL / 1 μM
CNL-P48T80P48T80 solution
solution of P48T80 DNA strand for usage with ENZ-80-1-R1-X or ENZ-80-1-Y1-X, P48T80 500 μL / 1 μM
CNL-P80T80-500P80T80 solution
solution of P80T80 DNA strand for usage with ENZ-80-1-R1-X or ENZ-80-1-Y1-X, P80T80 500 μL / 1 μM
CNL-QRF-B48-500cNL-B48-QRF solution
solution of complementary DNA lever for sequence B48 modified with a quenching molecule for the red fluorophore 500 μL / 1 μM
CNL-QRF-B96-500cNL-B96-QRF solution
solution of complementary DNA lever for sequence B96 modified with a quenching molecule for the red fluorophore 500 μL / 1 μM
CNL-QYF-B48-500cNL-B48-QYF solution
solution of complementary DNA lever for sequence B48 modified with a quenching molecule for the yellow fluorophore 500 μL / 1 μM
CNL-QYF-B96-500cNL-B96-QYF solution
solution of complementary DNA lever for sequence B96 modified with a quenching molecule for the yellow fluorophore 500 μL / 1 μM
CNL-QGF-B48-500cNL-B48-QGF solution
solution of complementary DNA lever for sequence B48 modified with a quenching molecule for the green fluorophore 500 μL / 1 μM
CNL-QGF-B96-500cNL-B96-QGF solution
solution of complementary DNA lever for sequence B96 modified with a quenching molecule for the green fluorophore 500 μL / 1 μM
SOL-PAS-1-510x Passivation solution
for passivation of chip surface (5 x 1 mL)
SOL-REG-12-1Regeneration solution
for regeneration of chip surface (1 x 12 mL)
SOL-REG-UR-12-1Urea solution
7 M urea (1 x 12 mL)

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