heliOS Software

Download 2022.2

We are pleased to announce that our latest 2022.2 release of heliOS is ready for you to download. It includes new features, enhancements and bug fixes. The latest heliOS version comes together with an improved set of heliOS methods and a powerful firmware update.

heliOS

version 2022.2.0 (124 MB)

heliOS Methods

version 2022.2 (5.3 MB)

heliX Firmware

version 5.255.6.1766 (1.5 GB)

heliX Quick Start Guide

version 4.1 (1.87MB)

Note: Before the update please read the Release Information Sheet.

Note: Before running a new heliOS version, a firmware update of your heliX device is necessary.

SYSTEM REQUIREMENTS
Supported Operating System I Windows 10

heliOS requires the .NET 6 Desktop Runtime. 
heliOS requires access to a postgreSQL database.

 

→ see install instructions

We are pleased to announce that our latest 2022.2 release of heliOS is ready for you to download. It includes a range of new features, enhancements and bug fixes and comes together with an improved set of heliOS methods and a powerful firmware update (5.255.6.1766).

As you might have noticed, we introduced year-based version numbers (2022.2, 2022.3 etc.) to simplify the naming and comparison of different versions.

Here is a list of the key features we have introduced 

  • A brand new set of methods has been developed that comprise enhanced fluidics and shorter run times. You can identify these methods by a green “verified” tag in your database.
  • A new buffer has been introduced. The maintenance buffer, connected to buffer tube 3, is a defined switchSENSE-compatible buffer (TE40). It is used in surface functionalization and passivation steps as well as chip status measurements.
  • We optimized the run time of our assays. For example, the run time of the chip test was cut in half and the requirement for an extra vial containing heliX® EDTA solution was eliminated.
  • You can now use two different running buffers of your choice within a single assay workflow. The running buffer can be specified for each assay and the software guides you through the set-up of the buffer compartment including the required buffer volumes. A priming step (formerly “change buffer) is added automatically whenever running buffers are switched.
  • In the (manual) analysis part, multiple measurement traces of the same type can be added as single measurement sources. This simplifies the handling of large data sets such as screening data, and enhances the performance.
  • After performing a data overview analysis a one-click snapshot option is now possible. Using this option, the entire overview is copied into your clipboard for further usage.

Methods

  • Grouping of composite parameters
  • Improved assay parameters display in an assay, after input of assay parameters in a composite method

Assays

  • Added new smart initial priming option “automatic” when starting an assay
  • Upgraded independence of assay and run parameters
  • Preserved assay parameters order in custom assays
  • Improved sample tray positions selection

Devices

  • Updated cleaning chip position in Clean & Sleep; position 5
  • Updated Clean & Sleep and priming logic to new buffer system
  • Updated ejection order: chip tray before sample tray when ejecting both trays
  • Order devices alphabetically

Experiments

  • Added connection between an experiment and it’s assay source (assay can be opened directly from the experiment)
  • Added a new tab in experiment view which contains all saved analyses of the experiment
  • Enabled selection of displayed trace type in experiment timeline
  • Replaced “TimeResolved” and “SumCounted” with “Dynamic” and “Static”, respectively in the measurements table overview
  • Added ability to copy electrodes images to clipboard

Analysis

  • Introduced rate-map plots for kinetics fit results
  • Improved fit stability
  • Improved fit descriptions
  • Added ability to create multiple alias elements in a single operation
  • Updated fit operation names across manual and automated analyses
  • Added gradient graph coloring option
  • Introduced multi-measurement sources to simplify handling of screening data in manual analyses
  • Added x-axis scaling factor to plots for manual unit adjustment
  • Added category plots for discrete x-axis data
  • Reduced clutter when selecting a trace within a plot
  • Added export of the whole data overview

Performance improvements:

  • Analysis plots
  • Experiment timeline
  • Opening of Assay
  • Composite methods with complex elements
  • Updating complex assays
  • Adding/Removing runs in an assay
  • Composite methods interface

 

General improvements:

  • Reduced chip test start voltage to -200mV
  • Improved error message for failed data import
  • Added highlighting of selected curves in a plot
  • Improved parameter editor dialog spacing
  • Improved parameter initialization for mono-phasic kinetics fits
  • Improved bottle labeling in wake up prime dialog
  • Improved stability of global kinetics fits
  • Improved description of assay parameters
  • Improved CSV import
  • Improved filtering functionalities in experiments and analysis

In this section you can find our main bugfixes. All reported crashes were also fixed.

  • Fixed issue with opening a method containing a branched method
  • Fixed issue preventing the exposal of composite method direction parameter
  • Fixed axis scaling factor
  • Fixed zooming in parameter configuration plots
  • Fixed axis titles refresh on data source change
  • Fixed assay parameter values transfer after duplicating an assay
  • Fixed issues with the sample distribution after position availability change
  • Fixed chip status analysis not showing all results when reopened
  • Fixed wake up and prime dialog
  • Fixed empty group row appearing on assays without any grouped run parameter
  • Fixed document corruption through files imported by higher software versions
  • Fixed buffer volume prediction update when adding or removing a priming step
  • Fixed initial sorting of measurements table in experiments
  • Fixed database corruptions caused by new versioning system
  • Fixed flickering live view
  • Fixed application of assay parameters in custom assay to all runs
  • Fixed missing tags in imported methods
  • Fixed DI water appearing as buffer proposal in wake up and prime
  • Fixed multiplex analysis graphs zooming issues
  • Fixed chip positioning for automatically inserted priming
  • Fixed kinetics association time parameter limits

In case you need help, please do not hesitate to contact our support team at support@dynamic-biosensors.com.

INSTALL INSTRUCTIONS

We recommend to always use the newest versions of heliOS and heliX firmware.
Please update first your heliX device with the latest firmware version before installing a new version of heliOS.

SYSTEM REQUIREMENTS

Supported Operating System I Windows 10

heliOS requires the .NET 6 Desktop Runtime.
heliOS requires access to a postgreSQL database.

heliX FIRMWARE UPDATE

Note: The installation of a new heliX firmware version must be performed from a computer which is connected to the heliX device.

Note: Skip this step if you are only interested in updating the heliOS version on a computer which is not used to control the heliX device.

  1. Ensure that the heliX device is switched on and connected to the control PC (directly or via network).
  2. Download the above listed version of the heliX firmware. We recommend to always use the newest version.
  3. Run the EXE installer on the control PC and follow the setup steps. You can find the IP address of your heliX in heliOS under Devices.
    After approx. 10 minutes the heliX will be restarted and ready to use.

INSTALLATION OF heliOS

Note: If heliOS is installed for the first time on a computer you need to first install the .NET 6 Desktop Runtime (see Installation of Microsoft .NET 6) and a PostgreSQL database (see Installation and set up of postgreSQL database).

 

  1. Download the above listed version of heliOS. We recommend to always use the newest version.
  2. Run the MSI installer and follow the setup steps.
  3. The first time you open heliOS on a computer you need to enter your license key (Settings → License).
    Copy and paste the license key into the intended input field and confirm.
  4. In addition to 3, the first time you are using heliOS you need to enter your database access data (Settings → Database).
  5. Now heliOS is ready to use and can, for example, be connected to your heliX device.

IMPORT OF heliOS METHODS

  1. Download the above listed heliOS methods.
  2. Unzip the downloaded file once. The unzipped folder contains a range of zipped heliOS methods. Do not unzip these files.
  3. Open heliOS and go to “Methods”.
  4. Click on “Import” in the top menu and select one or several heliOS methods (ZIP files) from the unzipped folder.
  5. Click on “Open”. Now your data base is equipped with the newest heliOS methods.

INSTALLATION OF MICROSOFT .NET 6

Note: heliOS requires the .NET 6 Desktop Runtime on your Windows operating system. If already installed you can skip this step.

 

  1. Download the .Net 6 Desktop Runtime from the link below. Select a version under “Run desktop apps” that matches the architecture of your Windows OS, either 32-bit (x86) or 64-bit (x64). https://dotnet.microsoft.com/download/dotnet/current/runtime
  2. Run the EXE installer and follow the setup steps.
  3. After the installation process has finished you are ready to install heliOS.

INSTALLATION AND SET UP OF A postgreSQL DATABASE

Note: heliOS requires a postgreSQL database either on a server in your local network or on your Windows operating system. If you do not have access to a network-based postgreSQL database you need to install one on your local computer. If already installed you can skip this step.

  1. Download postgreSQL from the link below. Select version 12.X for Windows x86-64.
    https://www.enterprisedb.com/downloads/postgres-postgresql-downloads
  2. Run the EXE installer and follow the setup steps. A detailed installation guide can be found here: https://www.enterprisedb.com/docs/supported-open-source/postgresql/installer/02_installing_postgresql_with_the_graphical_installation_wizard/01_invoking_the_graphical_installer/
    If you need help with setting up the postgrSQL database please ask your system administrator or contact our support team at support@dynamic-biosensors.com.
  3. After the installation process has finished you are ready to install heliOS.

In case you need help, please do not hesitate to contact our support team at support@dynamic-biosensors.com.

Questions?
Contact Us

Our support team is happy to help. 

support@dynamic-biosensors.com

+49 89 89 74 544-0

Lochhamer Str. 15, 82152 Martinsried/Planegg, Germany

M-F: 8am-5pm, S-S: Closed