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Application of the switchSENSE® Technique for the Study of Small Molecules’ (Ethidium Bromide and Selected Sulfonamide Derivatives) Affinity to DNA in Real Time

Read full Article Publication I September 15, 2022 Application of the switchSENSE® Technique for the Study of Small Molecules’ (Ethidium Bromide and Selected Sulfonamide Derivatives) Affinity to DNA in Real Time The discovery and introduction of the switchSENSE®...

The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination

Read full Article Publication I September 01, 2022 The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination DNA interstrand cross-links are tumor-inducing lesions that block DNA replication and transcription. When cross-links are...

Highly shape- and size-tunable membrane nanopores made with DNA

Read full Article Publication I April 28, 2022 Highly shape- and size-tunable membrane nanopores made with DNA Membrane nanopores are key for molecular transport in biology, portable DNA sequencing1,2,3,4, label-free single-molecule...

Molecular interactions with nucleic acids: Studying nucleic acid binding molecules with switchSENSE®

Download Brochure Brochure I January 24, 2022 Molecular interactions with nucleic acidsStudying nucleic acid binding molecules with switchSENSE®   Easy biosensor modification with specific nucleic acid sequences Real-time off-target binding information High...

The role of DNA nanostructures in the catalytic properties of an allosterically regulated protease

Read full Article Publication I January 5, 2022 The role of DNA nanostructures in the catalytic properties of an allosterically regulated protease DNA-scaffolded enzymes typically show altered kinetic properties; however, the mechanism behind this phenomenon is still...
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