
Webinar I September 17, 2024
DISCOVER reverse transcriptase activity: catalytic rates of nucleic acid-modifying enzymes
This is the seventh episode of our second season of the DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about cutting-edge drug discovery topics like bispecific antibodies, PROTACs or small molecules targeting RNA. We will show you how to characterize the respective molecular interactions in depth, how to create assays with remarkable biological similarity, low sample consumption, high versatility and exceptional ease-of-use. In this episode, we will look at a unique assay capability of the switchSENSE® technology: enzymatic activity. We will discuss how this biosensor technology cannot only be used to measure binding kinetics, but also to measure the catalytic activity of nucleic acid-modifying enzymes like reverse transcriptases or polymerases. Specifically, different reverse transcriptases were monitored for their ability to retain artificial base pairs.
If you are interested in another application, you can find all future episodes of this webinar series here
DISCOVER MOLECULAR INTERACTIONS webinar series