DISCOVER
MOLECULE-CELL
INTERACTIONS
Kinetics – Affinity – Avidity on Cells
heliXcyto
SLAS 2023 New Product Award Winner
Characterize molecules binding to membrane targets where they matter:
on cells.
Biosensor meets cytometry:
The heliXcyto is the first automated biosensor for single-cell Interaction Cytometry (scIC)
Unique data for membrane targets
No more mimicking and modeling. Real-Time Interaction Cytometry with the heliXcyto allows you to measure association kinetics, dissociation kinetics, half-life, affinity and avidity directly on cells, preserving the native folding, density, mobility and co-interactions of your molecule of interest by keeping it in its native environment.
→ Find out more about single-cell Interaction Cytometry.
Effortless and fast
From cell culture to interaction data in three simple steps with less than 1 h hands-on time thanks to automated workflows.
Compatible with any cell type
We use unique cell traps to physically retain the cells on the chip surface. You can trap any eukaryotic cell type you want within seconds, adherent or suspension, fixed or alive. There is no need for any modifications or specific receptors on the cells’ surface.
heliXcyto
unique design features
Modular connection to heliOS network
Autonomous device operation with embedded control system. Stable data transfer to control PC.
Optics
4 single photon fluorescence counters.
CCD camera for cell imaging.
Microfluidics
Advanced fluidics for rapid liquid exchange.
Reverse flow for chip regeneration.
Autosampler
Temperature controlled sample compartment.
Automatic chip loader
Automatic exchange of 5 chips.
RFID tags for seamless traceability.
Temperature control
Sample temperatures range from 15°- 40°C. Measurement in temperature gradient 10°C / min.
Applications
Applications in immuno-oncology, cell therapies, and many more
Biologics development
On-cell characterization of mono- and multi-specific antibodies, and other biologics.
Adoptive cell therapies
CAR-T cells, TCR engineering, NKs, new CMC modalities.
New targets
Biophysical analysis of so far inaccessible cell surface receptors (GPCRs, …).
heliX®
Product portfolio overview.
Contact Us
Discuss your specific needs with our specialists.