Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn
2024 I mAbs (open access)

Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1
2024 I MDPI (open access)

Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria
2024 I eLIFE (open access)

Reverse transcription as key step in RNA in vitro evolution with unnatural base pairs
2024 I RCS Chemical Biology (open access)

DNA origami traps for large viruses
2024 I Cell Reports Physical Science (open access)

Kinetic FRET to Measure Binding-Induced Conformational Changes of Nucleic Acids
2023 I ACS Sensors (open access)

Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction
2023 I Nucleic Acids Research (open access)

Synthetic Antigen-Conjugated DNA Systems for Antibody Detection and Characterization
2023 I ACS Sensors

Plant polygalacturonase structures specify enzyme dynamics and processivities to fine-tune cell wall pectins
2023 I The Plant Cell

Programmable multispecific DNA-origami-based T-cell engagers
2023 I Nature Nanotechnology

The Impact of N^ε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2
2023 I International Journal of Molecular Sciences (open access)

Kinetic analysis of ternary and binary binding modes of the bispecific antibody emicizumab
2022 I mAbs (open access)

Application of the switchSENSE^® Technique for the Study of Small Molecules’ (Ethidium Bromide and Selected Sulfonamide Derivatives) Affinity to DNA in Real Time
2022 I Journal of Physical Chemistry (open access)

The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination
2022 I Nature Structural & Molecular Biology

Multivalent Binding Kinetics Resolved by Fluorescence Proximity Sensing
2022 I Nature Portfolio (open access)

Sensitive Protein Detection Using Site-Specifically Oligonucleotide-Conjugated Nanobodies
2022 I Analytical Chemistry (open access)

Characterization of binding interactions of SARS-CoV-2 spike protein and DNA-peptide nanostructures
2022 I Scientific Reports

Highly shape- and size-tunable membrane nanopores made with DNA
2022 I Nature Nanotechnology (open access)

The role of DNA nanostructures in the catalytic properties of an allosterically regulated protease
2022 I Science Advances (open access)

Measuring Influenza A Virus and Peptide Interaction Using Electrically Controllable DNA Nanolevers
2021 I Advanced Materials Technologies (open access)

Tailored Biosensors for Drug Screening, Efficacy Assessment, and Toxicity Evaluation
2021 I ACS Sensors

Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
2021 I communications biology (open access)

Electrically Switchable Nanolever Technology for the Screening of Metal-Chelating Peptides in Hydrolysates
2021 I Journal of Agricultural and Food Chemistry

Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action
2021 I Nature Communications (open access)

Macromolecular interactions in vitro, comparing classical and novel approaches
2021 I European Biophysical Journal

Biophysical Studies of the Binding of Viral RNA with the 80S Ribosome Using switchSENSE
2021 I Methods in Molecular Biology book series (MIMB, volume 2263)

CMT2N-causing aminoacylation domain mutants enable Nrp1 interaction with AlaRS
2021 I PNAS (open access)

Standard operation procedure for switchSENSE DRX systems
2021 I European Biophysical Journal

switchSENSE Technology for Analysis of DNA Polymerase Kinetics
2021 I Methods in Molecular Biology book series (MIMB, volume 2247)

Affinity of chlordecone and chlordecol for human serum lipoproteins
2020 I Environmental Toxicology and Pharmacology

Sinorhizobium meliloti YrbA binds divalent metal cations using two conserved histidines 
2020 I Bioscience Reports (open access)

Oxidized glutathione promotes association between eukaryotic translation elongation factor 1Bγ and Ure2p glutathione transferase from Phanerochaete chrysosporium
2020 I The FEBS Journal (open access)

Nucleotide binding kinetics and conformational change analysis of tissue transglutaminase with switchSENSE
2020 I Analytical Biochemistry 

The trimer to monomer transition of Tumor Necrosis Factor-Alpha is a dynamic process that is significantly altered by therapeutic antibodies
2020 I Scientific Reports (open access)

Single-Molecule Sensing of DNA Intercalating Drugs in Water
2020 I Analytical Chemistry 

An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2
2020 I PNAS

Resolving Binding Events on the Multifunctional Human Serum Albumin
2020 I ChemMedChem (open access) 

Preparation of single- and double-oligonucleotide antibody conjugates and their application for protein analytics
2020 I Scientific Reports (open access)

Validation of the Slow Off‐Kinetics of Sirtuin‐Rearranging Ligands (SirReals) by Means of Label‐Free Electrically Switchable Nanolever Technology
2020 I ChemBioChem

A compact nanobody-DNAzyme conjugate enables antigen detection and signal amplification
2020 I New Biotechnology

CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells
2019 I PNAS

A DNA-Based Biosensor Assay for the Kinetic Characterization of Ion-Dependent Aptamer Folding and Protein Binding 
2019 I molecules (open access)

Triazine-Modified 7-Deaza-2′-deoxyadenosines: Better Suited for Bioorthogonal Labeling of DNA by PCR than 2′-Deoxyuridines
2019 I Bioconjugate Chemistry

Specific inhibition of splicing factor activity by decoy RNA oligonucleotides
2019 I Nature Communications (open access)

Dissecting FOXP2 oligomerization and DNA binding
2019 I Angewandte Chemie 

Tailored peptide phenyl esters block ClpXP proteolysis by an unusual breakdown into a heptamer‐hexamer assembly
2019 I Angewandte Chemie

RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not
2019 I eLIFE Magazine (open access)

Utilization of Staphylococcal Immune Evasion Protein Sbi as a Novel Vaccine Adjuvant
2019 I frontiers in Immunology (open access)

Magnesium-Dependent Electrical Actuation and Stability of DNA Origami Rods
2018 I ACS Appl. Mater. Interfaces

Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus
2018 I Journal of Medicinal Chemistry

Structural and Kinetic Profiling of Allosteric Modulation of Duplex DNA Induced by DNA‐Binding Polyamide Analogues
2018 I CHEMISTRY A European Journal

Assembly and Characterization of a Slingshot DNA Nanostructure for the Analysis of Bivalent and Bispecific Analytes with Biosensors
2018 I Langmuir

XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining
2018 I Nature Structural & Molecular Biology

Fungal Glutathione Transferases as Tools to Explore the Chemical Diversity of Amazonian Wood Extractives
2018 I ACS Sustainable Chemistry & Engineering

DNA primer extension with cyclopropenylated 7‐deaza‐2’‐deoxyadenosine and efficient bioorthogonal labeling in vitro and in living cells
2018 I ChemBioChem

mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases
2018 I Molecular Cell
Highlighted in Tailing Off: PABP and CNOT Generate Cycles of mRNA Deadenylation 2018 I Molecular Cell

ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase
2018 I Nature

A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding
2018 I Journal of Biological Chemistry (open access)

Preclinical Development of a Novel, Orally-Administered Anti-Tumour Necrosis Factor Domain Antibody for the Treatment of Inflammatory Bowel Disease
2018 I Scientific Reports (open access)

Mapping the sugar dependency for rational generation of a DNA-RNA hybrid-guided Cas9 endonuclease
2017 I Nature Communications (open access)

Electrical Actuation of a DNA Origami Nanolever on an Electrode
2017 I Journal of the American Chemical Society

Physical interaction between the strawberry allergen Fra a 1 and an associated partner FaAP: Interaction of Fra a 1 proteins and FaAP
2017 I PROTEINS

Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy
2017 I Nucleic Acids Research

Structural study of the Fox-1 RRM protein hydration reveals a role for key water molecules in RRM-RNA recognition
2017 I Nucleic Acids Research

switchSENSE: A new technology to study protein-RNA interactions
2017 I Methods

Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon
2017 I Nucleic Acids Research (open access)

The long zinc finger domain of PRDM9 forms a highly stable and long-lived complex with its DNA recognition sequence

2017 I Journal Chromosome Research

Specialized interfaces of Smc5/6 control hinge stability and DNA association
2017 I Nature Communications (open access)

Polymerase/DNA Interactions and Enzymatic Activity: Multiparameter Analysis with Electroswitchable Biosurfaces
2015 I Scientific Reports (open access)

Detection of the Carcinogenic Water Pollutant Benzo[a]pyrene with an Electro-Switchable Biosurface
2015 I Analytical Chemistry

Molecular Dynamics of DNA−Protein Conjugates on Electrified Surfaces: Solutions to the Drift-Diffusion Equation
2014 I Journal of Physical Chemistry B

Protein analysis by time-resolved measurements with an electro-switchable DNA chip
2013 I Nature Communications (open access)

Covalent attachment of functionalized cardiolipin on a biosensor gold surface allows repetitive measurements of anticardiolipin antibodies in serum
2013 I Analytical and Bioanalytical Chemistry

Sensing with electro-switchable biosurfaces
2012 I Bioanalytical Reviews

Messung molekularer Interaktion mit dynamischen Oberflächensensoren
2012 I BIOspektrum

Quantitation of Affinity, Avidity, and Binding Kinetics of Protein Analytes with a Dynamically Switchable Biosurface
2012 I Journal of the American Chemical Society

Leichte Proteine schwingen besser
2010 I Nachrichten aus der Chemie

Analyse von Biomolekülen mit aktiv bewegten Nano-Oberflächen
2010 I Laborwelt

Conformations of End-Tethered DNA Molecules on Gold Surfaces:
Influences of Applied Electric Potential, Electrolyte Screening, and Temperature
2010 I Journal of the American Chemical Society

Platform for in situ real-time measurement of protein-induced conformational changes of DNA
2009 I Proc. Nat. Acad. Sci. Am.

Dynamics of end grafted DNA molecules and possible biosensor applications
2009 I phys. stat. sol. (a)

Electrical Manipulation of DNA on Metal Surfaces
2008 I NanoBio Technology: BioInspired devices and materials of the future

Switchable DNA interfaces for the highly sensitive detection of label-free DNA targets
2007 I Proc. Nat. Acad. Sci. Am.

Controlling the surface density of DNA on gold by electrically induced desorption
2007 I Biosensors and Bioelectronics

Electrical manipulation of oligonucleotides grafted to charged surfaces
2006 I Organic & Biomolecular Chemistry

The Role of Surface Charging during the Coadsorption of Mercaptohexanol to DNA Layers on Gold: Direct Observation of Desorption and Layer Reorientation
2006 I Langmuir

Dissimilar Kinetic Behavior of Electrically Manipulated Single- and Double-Stranded DNA Tethered to a Gold Surface
2006 I Biophysical Journal

Dynamic Electrical Switching of DNA Layers on a Metal Surface
2004 I Nano Letters

Structural Properties of Oligonucleotide Monolayers on Gold Surfaces Probed by Fluorescence Investigations
2004 I Langmuir