switchSENSE®
eLearning Center
We cover an array of various, different applications.
Browse through publications, application notes,
tutorials, and more.
Molecule Type
Analytical Method
DISCOVER small molecule-induced protein conformational changes using DNA origami nanolevers
Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn
DISCOVER screening of PROTACs/molecular glues: ternary complex analysis with induced proximity
Real-time measurement of DNA polymerase activity and inhibition with switchSENSE® and the heliX® biosensor
Reverse transcription as key step in RNA in vitro evolution with unnatural base pairs
Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria
Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1
DISCOVER therapeutic antibodies: kinetics of antibody-drug conjugates measured directly on cells
DISCOVER protein-DNA conjugate purification: Effortless conjugate preparation, purification, and analysis with the proFIRE®
DNA origami traps for large viruses
Kinetic FRET Assay to Measure Binding-Induced Conformational Changes of Nucleic Acids
Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction
DISCOVER high throughput kinetic characterization of engineered multivalent peptide based inhibitors
DISCOVER protein conformational changes with electrically actuated DNA origami nanolevers
heliX Adapter Chip Storage and Handling
DISCOVER RNA protein interactions: Resolve multidomain interactions and RNA looping.
Programmable multispecific DNA-origami-based T-cell engagers
Synthetic Antigen-Conjugated DNA Systems for Antibody Detection and Characterization
DISCOVER complex membrane targets: measure binding to GPCRs, ion channels and more directly on cells
switchSENSE®: comprehensive characterization of molecule-molecule interactions
Plant polygalacturonase structures specify enzyme dynamics and processivities to fine-tune cell wall pectins
DISCOVER small molecule induced aptamer folding: a biosensor assay to detect structural changes
DISCOVER bispecific antibodies: straightforward characterization of mode of action & avidity effects
