switchSENSE®

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Real-time measurement of DNA polymerase activity and inhibition with switchSENSE® and the heliX® biosensor

Real-time measurement of DNA polymerase activity and inhibition with switchSENSE® and the heliX® biosensor

Reverse transcription as key step in RNA in vitro evolution with unnatural base pairs

Reverse transcription as key step in RNA in vitro evolution with unnatural base pairs

Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria

Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria

Kinetic FRET Assay to Measure Binding-Induced Conformational Changes of Nucleic Acids

Kinetic FRET Assay to Measure Binding-Induced Conformational Changes of Nucleic Acids

Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction

Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction

DISCOVER high throughput kinetic characterization of engineered multivalent peptide based inhibitors

DISCOVER high throughput kinetic characterization of engineered multivalent peptide based inhibitors

DISCOVER protein conformational changes with electrically actuated DNA origami nanolevers

DISCOVER protein conformational changes with electrically actuated DNA origami nanolevers

DISCOVER RNA protein interactions: Resolve multidomain interactions and RNA looping.

DISCOVER RNA protein interactions: Resolve multidomain interactions and RNA looping.

Programmable multispecific DNA-origami-based T-cell engagers

Programmable multispecific DNA-origami-based T-cell engagers

Synthetic Antigen-Conjugated DNA Systems for Antibody Detection and Characterization

Synthetic Antigen-Conjugated DNA Systems for Antibody Detection and Characterization

DISCOVER complex membrane targets: measure binding to GPCRs, ion channels and more directly on cells

DISCOVER complex membrane targets: measure binding to GPCRs, ion channels and more directly on cells

switchSENSE®:  comprehensive characterization of molecule-molecule interactions

switchSENSE®: comprehensive characterization of molecule-molecule interactions

Plant polygalacturonase structures specify enzyme dynamics and processivities to fine-tune cell wall pectins

Plant polygalacturonase structures specify enzyme dynamics and processivities to fine-tune cell wall pectins

DISCOVER small molecule induced aptamer folding: a biosensor assay to detect structural changes

DISCOVER small molecule induced aptamer folding: a biosensor assay to detect structural changes

DISCOVER bispecific antibodies: straightforward characterization of mode of action & avidity effects

DISCOVER bispecific antibodies: straightforward characterization of mode of action & avidity effects

Kinetic analysis of ternary and binary binding modes of the bispecific antibody emicizumab

Kinetic analysis of ternary and binary binding modes of the bispecific antibody emicizumab

The Impact of N<sup>ε</sup>-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2

The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2

DNA Y-structure: Analysis of ternary complex formation

DNA Y-structure: Analysis of ternary complex formation

Application of the switchSENSE® Technique for the Study of Small Molecules’ (Ethidium Bromide and Selected Sulfonamide Derivatives) Affinity to DNA in Real Time

Application of the switchSENSE® Technique for the Study of Small Molecules’ (Ethidium Bromide and Selected Sulfonamide Derivatives) Affinity to DNA in Real Time

The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination

The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination

Characterization of binding interactions of SARS-CoV-2 spike protein and DNA-peptide nanostructures

Characterization of binding interactions of SARS-CoV-2 spike protein and DNA-peptide nanostructures