DISCOVER
MOLECULAR INTERACTIONS
dynamicBIOSENSORS 2023 WEBINAR SERIES I NEXT WEBINAR JUNE 14, 2023
Find the right assay for your research project.
The DISCOVER MOLECULAR INTERACTIONS webinar series is designed to help you find the right assay for your research project!
Each month we will talk about cutting-edge drug discovery topics like bispecific antibodies, PROTACs or RNA-binding small molecules.
We will show you how to characterize the respective molecular interactions in depth, how to create assays with remarkable biological similarity, low sample consumption, high versatility and exceptional ease-of-use.
You are a switchSENSE® or RT-IC user and want to learn more about specific applications?
You use a different technology like SPR and are curious about alternatives?
You do not use a biophysical technology and want to learn more about how to advance your research project with kinetic measurements?
We’ve got you covered!
Explore our webinar topics below and register today:
DISCOVER PROTAC ternary complex formation: an induced-proximity assay for PROTAC hit screening
June 14, 2023
→ REGISTER for the 10:00 AM (CET) session
→ REGISTER for the 07:00 PM (CET) session
In this webinar we will introduce a cutting-edge biophysical assay designed for the analysis of PROTAC ternary complex formation. The assay employs an induced-proximity set-up which enables you to control the local concentration and stoichiometry of both ligands. It yields precise kinetic data for binary as well as ternary interactions to characterize cooperativity effects, and it can be used to screen homo- or heterospecific PROTACs.
DISCOVER complex membrane targets: measure binding to GPCRs, ion channels, and more directly on living cells
July 12, 2023
→ REGISTER for the 10:00 AM (CET) session
→ REGISTER for the 07:00 PM (CET) session
Transmembrane proteins like GPCRs and ion channels often depend on their native environment and correct transmembrane domain folding in order to exert their functions.
Real-Time Interaction Cytometry enables you to measure interactions of molecules with these complex transmembrane targets directly on living cells. That way you can be sure to study a functional protein and can avoid tedious isolation and refolding protocols.
DISCOVER RNA-protein interactions: resolve multidomain interactions and RNA-looping
August 09, 2023
→ REGISTER for the 10:00 AM (CET) session
→ REGISTER for the 07:00 PM (CET) session
Interactions often go beyond the simple 1:1 binding. In this webinar you will learn how to take your kinetic analysis to the next level and characterize the contributions of different protein domains to the overall interaction.
We will also discuss molecules that induce RNA-looping and how you can detect these structural changes in a switchSENSE® assay.
Recordings of previous episodes
DISCOVER more applications and topics:
You can find recordings of all our previous webinar episodes in our YouTube webinar playlist.