Read full Article Publication I July 15, 2015 Polymerase/DNA interactions and enzymatic activity: multiparameter analysis with electroswitchable biosurfaces The engineering of high-performance enzymes for future sequencing and PCR technologies as well as the...
Read App Note App Note I January 26, 2017 switchSENSE® for the characterization of polymerases switchSENSE® is the first and only chip-based biosensor that employs electro-switchable biosurfaces (ESB) for the biophysical analysis of molecular interactions. Two signals...
Read App Note App Note I January 17, 2016 Real-time measurements of DNA exonucleases The activities of the 5’→3’ exonucleases T5 exonuclease and Lambda exonuclease could be analyzed using a switchSENSE molecular ruler assay. The assay can be applied for evaluating...
Read App Note App Note I January 25, 2014 Nanolever temperature stabilitystandard DNA nanolever The oligodeoxynucleotides used as standard nanolevers have been selected to maintain their double stranded conformation even at high temperatures and can be used up to 70°C...
Read App Note App Note I January 15, 2014 Inhibitor induced shifts in the thermal stability of carbonic anhydrase The thermal stability of proteins can be investigated by measuring the switching dynamics of proteinnanolever conjugates as a function of temperature....
