Read full Article Publication I April 28, 2022 Highly shape- and size-tunable membrane nanopores made with DNA Membrane nanopores are key for molecular transport in biology, portable DNA sequencing1,2,3,4, label-free single-molecule...
watch tutorial Tutorial I May 18, 2022 Tight Binders Tutorial Affinity becomes challenging to measure for so-called “tight-binding” ligands that possess low dissociation rate constants (kD, or “off-rate” constant) where progress toward equilibrium is inversely...
Download Brochure Brochure I October 20, 2021 Kinetics of multispecific binders:Analysis of cooperative binding with switchSENSE® switchSENSE® FEATURES: Straightforward sensor functionalization with two different antigens. Variable ligand density to control...
Read full Article Publication I June 18, 2021 Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action The receptor tyrosine kinase HER2 acts as oncogenic driver in numerous cancers. Usually, the gene is amplified, resulting in receptor...
watch tutorial Tutorial I April 23, 2021 heliX® Bivalent and Bispecific Binders Tutorial Research continues to advance a growing number of bispecific binders for therapeutic purposes. These bivalent constructs that serve as molecular bridges to link together two...