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Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn

Read full Article Publication I June 7, 2024 Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn Monoclonal antibodies (mAbs) as therapeutics necessitate favorable pharmacokinetic properties, including extended...

DISCOVER screening of PROTACs/molecular glues: ternary complex analysis with induced proximity

View Webinar Webinar I May 14, 2024 DISCOVER screening of PROTACs/molecular glues: ternary complex analysis with induced proximity   This is the fourth episode of our second season of the DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about...

Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1

Read full Article Publication I May 2, 2024 Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1 The optimization of the affinity of monoclonal antibodies is crucial for the development of drug candidates, as...

DISCOVER therapeutic antibodies: kinetics of antibody-drug conjugates measured directly on cells

View Webinar Webinar I April 17, 2024 DISCOVER therapeutic antibodies: kinetics of antibody-drug conjugates measured directly on cells This is the third episode of our second season of the DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about...

DISCOVER protein-DNA conjugate purification: Effortless conjugate preparation, purification, and analysis with the proFIRE®

View Webinar Webinar I March 18, 2024 DISCOVER protein-DNA conjugate purification: Effortless conjugate preparation, purification, and analysis with the proFIRE® This is the second episode of the second season of the DISCOVER MOLECULAR INTERACTIONS webinar series....
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