Read App Note App Note I November 21, 2018 Measuring ligation activity of T4 DNA ligase on nicked DNA with switchSENSE® DNA ligases fulfill essential functions in DNA replication, DNA repair, and are standard tools in molecular biology labs. Here, we describe a...
Read full Article Publication I October 5, 2018 XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining The Ku70–Ku80 (Ku) heterodimer binds rapidly and tightly to the ends of DNA double-strand breaks and recruits factors of the...
Read full Article Publication I September 17, 2018 DNA Primer Extension with Cyclopropenylated 7-Deaza-2′-deoxyadenosine and Efficient Bioorthogonal Labeling in Vitro and in Living Cells A deoxyadenosine triphosphate (dATP) analogue for DNA labeling was...
Read full Article Publication I June 21, 2018 mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases Translation and decay of eukaryotic mRNAs is controlled by shortening of the poly(A) tail and release of the...
Read full Article Publication I November 7, 2017 Electrical actuation of a DNA origami nanolever on an electrode Development of electrically powered DNA origami nanomachines requires effective means to actuate moving origami parts by externally applied electric...