View Webinar Webinar I May 14, 2024 DISCOVER screening of PROTACs/molecular glues: ternary complex analysis with induced proximity This is the fourth episode of our second season of the DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about...
Read More App Note Real-time measurement of DNA polymerase activity and inhibition with switchSENSE® and the heliX® biosensor Polymerases play a key role in all living cells for the replication and preservation of genetic information. They are also interesting drug...
Read full Article Publication I April 23, 2024 Reverse transcription as key step in RNA in vitro evolution with unnatural base pairs Unnatural base pairs (UBPs) augment the chemical diversity of artificial nucleic acids and can thus enable the generation of new...
Read full Article Publication I February 16, 2024 Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria The RNA recognition motif (RRM) is the most common RNA-binding protein domain identified in nature. However,...
Read full Article Publication I May 2, 2024 Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1 The optimization of the affinity of monoclonal antibodies is crucial for the development of drug candidates, as...
