switchSENSE® for characterization of polymerases

Read App Note App Note I January 26, 2017 switchSENSE® for the characterization of polymerases switchSENSE® is the first and only chip-based biosensor that employs electro-switchable biosurfaces (ESB) for the biophysical analysis of molecular interactions. Two signals...

Quantifying DNA exonuclease activity

Read App Note App Note I December 22, 2016 Quantifying DNA exonuclease activity using a switchSENSE® hybridization assay  The activity of the T5 exonuclease is quantified in a simple and quick workflow. This study demonstrates that the presence of T5 exonuclease down...

Real-time measurements of DNA exonucleases

Read App Note App Note I January 17, 2016 Real-time measurements of DNA exonucleases The activities of the 5’→3’ exonucleases T5 exonuclease and Lambda exonuclease could be analyzed using a switchSENSE molecular ruler assay. The assay can be applied for evaluating...