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XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining

Read full Article Publication I October 5, 2018 XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining The Ku70–Ku80 (Ku) heterodimer binds rapidly and tightly to the ends of DNA double-strand breaks and recruits factors of the...

Assembly and Characterization of a Slingshot DNA Nanostructure for the Analysis of Bivalent and Bispecific Analytes with Biosensors

Read full Article Publication I October 1, 2018 Assembly and Characterization of a Slingshot DNA Nanostructure for the Analysis of Bivalent and Bispecific Analytes with Biosensors The characterization of novel therapeutic antibodies with multivalent or multispecific...

Fungal Glutathione Transferases as Tools to Explore the Chemical Diversity of Amazonian Wood Extractives

Read full Article Publication I August 25, 2018 ​Fungal Glutathione Transferases as Tools to Explore the Chemical Diversity of Amazonian Wood Extractives The natural durability of wood is linked to its chemical composition and in particular the presence of metabolites...

mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases

Read full Article Publication I June 21, 2018 mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases Translation and decay of eukaryotic mRNAs is controlled by shortening of the poly(A) tail and release of the...

ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase

Read full Article Publication I May 16, 2018 ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase Editing domains of aminoacyl tRNA synthetases correct tRNA charging errors to maintain translational fidelity. A mutation in the editing domain of...
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