Read full Article Publication I June 7, 2024 Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn Monoclonal antibodies (mAbs) as therapeutics necessitate favorable pharmacokinetic properties, including extended...
Read full Article Publication I May 2, 2024 Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1 The optimization of the affinity of monoclonal antibodies is crucial for the development of drug candidates, as...
Read More App Note switchSENSE® Compatibility Sheet The switchSENSE® compatibility provides an overview on different conditions switchSENSE® measurements can be performed in. ...
Read full Article Publication I April 01, 2021 Macromolecular interactions in vitro, comparing classical and novel approaches Biophysical quantification of protein interactions is central to unveil the molecular mechanisms of cellular processes. Researchers can choose...
Read full Article Publication I March 27, 2021 Standard operation procedure for switchSENSE DRX systems There is currently a large panel of technologies available to address molecular interactions in vitro. Each technology presents individual advantages and drawbacks,...
