Read full Article Publication I August 17, 2023 Programmable multispecific DNA-origami-based T-cell engagers Multispecific antibodies have emerged as versatile therapeutic agents, and therefore, approaches to optimize and streamline their design and assembly are...
Read full Article Publication I July 18, 2023 Synthetic Antigen-Conjugated DNA Systems for Antibody Detection and Characterization Antibodies are among the most relevant biomolecular targets for diagnostic and clinical applications. In this Perspective, we provide a...
Read full Article Publication I May 18, 2023 Plant polygalacturonase structures specify enzyme dynamics and processivities to fine-tune cell wall pectins Polygalacturonases (PGs) fine-tune pectins to modulate cell wall chemistry and mechanics, impacting plant...
Read full Article Publication I December 1, 2022 Kinetic analysis of ternary and binary binding modes of the bispecific antibody emicizumab The binding properties of bispecific antibodies (bsAb) are crucial for their function, especially when two antigens are targeted...
Read full Article Publication I January 13, 2023 The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2 In addition to the classic functions of proteins, such as acting as a biocatalyst or binding partner, the conformational...