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Highly shape- and size-tunable membrane nanopores made with DNA

Read full Article Publication I April 28, 2022 Highly shape- and size-tunable membrane nanopores made with DNA Membrane nanopores are key for molecular transport in biology, portable DNA sequencing1,2,3,4, label-free single-molecule...

Multivalent Binding Kinetics Resolved by Fluorescence Proximity Sensing

Read full Article Publication I April 28, 2022 Multivalent Binding Kinetics Resolved by Fluorescence Proximity Sensing Multivalent protein interactors are an attractive modality for probing protein function and exploring novel pharmaceutical strategies. The throughput...

The role of DNA nanostructures in the catalytic properties of an allosterically regulated protease

Read full Article Publication I January 5, 2022 The role of DNA nanostructures in the catalytic properties of an allosterically regulated protease DNA-scaffolded enzymes typically show altered kinetic properties; however, the mechanism behind this phenomenon is still...

Measuring Influenza A Virus and Peptide Interaction Using Electrically Controllable DNA Nanolevers

Read full Article Publication I October  29, 2021 Measuring Influenza A Virus and Peptide Interaction Using Electrically Controllable DNA Nanolevers Electrically controllable deoxyribonuclic acid (DNA) nanolevers are used to investigate the binding interaction between...

Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion

Read full Article Publication I September 07, 2021 Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion Many cadherin family proteins are associated with diseases such as cancer. Since cell adhesion requires homodimerization...
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