Read full Article Publication I December 7, 2023 Kinetic FRET Assay to Measure Binding-Induced Conformational Changes of Nucleic Acids The interaction of small molecules or proteins with RNA or DNA often involves changes in the nucleic acid (NA) folding and structure....
Read full Article Publication I November 27, 2023 Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction The classical Non-Homologous End Joining (c-NHEJ) pathway is the predominant process in mammals...
Read full Article Publication I August 17, 2023 Programmable multispecific DNA-origami-based T-cell engagers Multispecific antibodies have emerged as versatile therapeutic agents, and therefore, approaches to optimize and streamline their design and assembly are...
Read full Article Publication I July 18, 2023 Synthetic Antigen-Conjugated DNA Systems for Antibody Detection and Characterization Antibodies are among the most relevant biomolecular targets for diagnostic and clinical applications. In this Perspective, we provide a...
Read full Article Publication I May 18, 2023 Plant polygalacturonase structures specify enzyme dynamics and processivities to fine-tune cell wall pectins Polygalacturonases (PGs) fine-tune pectins to modulate cell wall chemistry and mechanics, impacting plant...