How much sample do I need for my experiment?

We know your samples are precious. So we optimized the switchSENSE® technology for minimum sample consumption. You will need approximately 5 pmol ligand per experimental run. Of course, this highly depends on your exact experimental conditions. You can always contact...

Can I perform high-throughput screenings with switchSENSE®?

The heliX+ instruments were designed to fit your specific needs. You can easily scale up your throughput by combining as many heliX+ modules as you require. This modular design offers high versatility – you can combine heliX units in one heliOS network, operate them...

Can I multiplex with switchSENSE®?

Yes, with a heliX+ you can multiplex up to four interactions due to four single-photon detectors. Two colors can be detected on each of the two sensor spots. And if you want to scale up your throughput, you can combine several heliX+ instruments in one...

Can I examine multispecific binders with switchSENSE®?

Yes! You can either functionalize the surface with two different ligands and differentiate between affinity and avidity. Or you can use the specific DNA Y-structure to examine bispecific analytes, ternary complex formation or protein dimerization.

How many samples can I measure simultaneously?

The heliX+ chip has two sensor spots and each sensor spot allows for two-color detection, enabling you to simultaneously detect four signals by four single-photon detectors. You can either multiplex four interactions or use one spot for real-time referencing. Please...