Read App Note App Note I January 7, 2019 Reverse Transcriptase binding and activity assays with switchSENSE® Reverse transcriptase (RT) is an enzyme found in retroviruses that catalyzes the conversion of single-stranded RNA into double-stranded cDNA. This function of...
Read App Note App Note I November 21, 2018 Measuring ligation activity of T4 DNA ligase on nicked DNA with switchSENSE® DNA ligases fulfill essential functions in DNA replication, DNA repair, and are standard tools in molecular biology labs. Here, we describe a...
Read full Article Publication I September 17, 2018 DNA Primer Extension with Cyclopropenylated 7-Deaza-2′-deoxyadenosine and Efficient Bioorthogonal Labeling in Vitro and in Living Cells A deoxyadenosine triphosphate (dATP) analogue for DNA labeling was...
Read full Article Publication I November 20, 2017 Mapping the sugar dependency for rational generation of a DNA-RNA hybrid-guided Cas9 endonuclease The CRISPR–Cas9 RNA-guided endonuclease system allows precise and efficient modification of complex genomes and is...
Read full Article Publication I July 27, 2017 Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy While having multiple aminoacyl-tRNA synthetases implicated in Charcot-Marie-Tooth (CMT) disease suggests a...
