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Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus

Read full Article Publication I December 7, 2018 Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus Celastrol is a natural pentacyclic triterpene used in traditional Chinese...

Biophysical characterization of bispecific antibodies developed for enhancement of dual-targeting specificity with switchSENSE®

DOWNLOAD BROCHURE Brochure I December 14, 2018 Biophysical characterization of bispecific antibodies developed for enhancement of dual-targeting specificity with switchSENSE® The measurement of kinetic rates and avidity binding in the simultaneous engagement of two...

Sizing Analysis of the Ubiquitin / E1-E2-E3 Complex using switchSENSE® technology

Read App Note App Note I November 12, 2018 Sizing Analysis of the Ubiquitin / E1-E2-E3 Complex using switchSENSE® technology  During the posttranslational process of ubiquitination, the small regulatory protein ubiquitin (Ub) is covalently attached to a lysine residue...

Structural and Kinetic Profiling of Allosteric Modulation of Duplex DNA Induced by DNA-Binding Polyamide Analogues

Read full Article Publication I November 8, 2018 Structural and Kinetic Profiling of Allosteric Modulation of Duplex DNA Induced by DNA-Binding Polyamide Analogues A combined structural and quantitative biophysical profile of the DNA binding affinity, kinetics and...

switchSENSE® Bispecific Antibodies

Animation switchSENSE® Bispecific Antibodies https://youtu.be/_FwYM3OmcIo...
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