Association rate of two equimolar reactants in solution

Read App Note App Note I August 27, 2016 Association rate of two equimolar reactants in solution In this theory note we describe the derivation of the association rate constant kon from general reaction kinetics for two equimolar reactants in solution.   Download...

List of protein hydrodynamic diameters

App Note I May 17, 2017 List of protein hydrodynamic diameters DH ProteinMolecular weightDH measured with switchSENSE® (i)Dh calculated from PDB file (ii)PDB codeStructure anti-human Fab fragment050 kDa06.6 nm07.2 nm3WD5 anti-human IgG150 kDa12.7 nm11.2 nm1IGT...

Real-time measurement of nickel ion chelation kinetics

Read App Note App Note I January 22, 2016 Real-time measurement of nickel ion chelation kinetics Nitrilotriacetic acid (NTA) is a common chelating agent, which forms coordination compounds with metal ions (chelates) such as Ni2+, Cu2+ and Co2+. It is primarily used...

Real-time measurements of DNA exonucleases

Read App Note App Note I January 17, 2016 Real-time measurements of DNA exonucleases The activities of the 5’→3’ exonucleases T5 exonuclease and Lambda exonuclease could be analyzed using a switchSENSE molecular ruler assay. The assay can be applied for evaluating...