Read full Article Publication I March 11, 2020 Resolving Binding Events on the Multifunctional Human Serum Albumin Physiological processes rely on initial recognition events between cellular components and other molecules or modalities. Biomolecules can have multiple...
Read full Article Publication I September 9, 2019 CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells Aminoacyl-transfer RNA (tRNA) synthetases (aaRSs) are the largest protein...
Read full Article Publication I August 8, 2019 A DNA-based biosensor assay for the kinetic characterization of ion-dependent aptamer folding and protein binding Therapeutic and diagnostic aptamers are nucleic acid oligomers designed to bind tightly and specifically...
Read full Article Publication I May 29, 2019 A Step-by-Step Guide to Study Protein–RNA Interactions Protein–RNA complex formation is at the center of RNA metabolism and leads to the modulation of protein and RNA functions. We propose here a step-by-step guide to...
Read full Article Publication I December 11, 2020 Triazine-Modified 7-Deaza-2′-deoxyadenosines: Better Suited for Bioorthogonal Labeling of DNA by PCR than 2′-Deoxyuridines 6-Ethynyl-1,2,4-triazine is a small bioorthogonally reactive group we applied for fluorescent...