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Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn

Read full Article Publication I June 7, 2024 Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn Monoclonal antibodies (mAbs) as therapeutics necessitate favorable pharmacokinetic properties, including extended...

Real-time measurement of DNA polymerase activity and inhibition with switchSENSE® and the heliX® biosensor

Read More App Note Real-time measurement of DNA polymerase activity and inhibition with switchSENSE® and the heliX® biosensor Polymerases play a key role in all living cells for the replication and preservation of genetic information. They are also interesting drug...

Reverse transcription as key step in RNA in vitro evolution with unnatural base pairs

Read full Article Publication I April 23, 2024 Reverse transcription as key step in RNA in vitro evolution with unnatural base pairs Unnatural base pairs (UBPs) augment the chemical diversity of artificial nucleic acids and can thus enable the generation of new...

Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria

Read full Article Publication I February 16, 2024 Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria The RNA recognition motif (RRM) is the most common RNA-binding protein domain identified in nature. However,...

DISCOVER protein-DNA conjugate purification: Effortless conjugate preparation, purification, and analysis with the proFIRE®

View Webinar Webinar I March 18, 2024 DISCOVER protein-DNA conjugate purification: Effortless conjugate preparation, purification, and analysis with the proFIRE® This is the second episode of the second season of the DISCOVER MOLECULAR INTERACTIONS webinar series....
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