Read full Article Publication I December 7, 2023 Kinetic FRET Assay to Measure Binding-Induced Conformational Changes of Nucleic Acids The interaction of small molecules or proteins with RNA or DNA often involves changes in the nucleic acid (NA) folding and structure....
Read full Article Publication I November 27, 2023 Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction The classical Non-Homologous End Joining (c-NHEJ) pathway is the predominant process in mammals...
Download Brochure Brochure I May 15, 2024 switchSENSE® comprehensive characterization of molecule-molecule interactions This brochure explains how to analyze interactions of any molecule of your interest, ranging from small molecules to antibodies. switchSENSE®...
Read More App Note switchSENSE® Compatibility Sheet The switchSENSE® compatibility provides an overview on different conditions switchSENSE® measurements can be performed in. ...
Read full Article Publication I October 27, 2022 Structural basis for Cas9 off-target activity The target DNA specificity of the CRISPR-associated genome editor nuclease Cas9 is determined by complementarity to a 20-nucleotide segment in its guide RNA. However, Cas9...
