Read full Article Publication I September 15, 2020 Nucleotide binding kinetics and conformational change analysis of tissue transglutaminase with switchSENSE® Function, activity, and interactions of proteins crucially depend on their three-dimensional structure and...
Read full Article Publication I August, 2020 DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease Repair of covalent DNA-protein crosslinks (DPCs) by DNA-dependent proteases has emerged as an essential genome maintenance mechanism required...
Read full Article Publication I July 2, 2020 Molecular Dynamics to Elucidate the DNA-Binding Activity of AlpZ, a Member of the Gamma-Butyrolactone Receptor Family in Streptomyces ambofaciens Signaling molecule receptors play a central role in quorum sensing and in the...
Download Brochure Brochure I April 29, 2020 proFIRE® flyer Imagine an effortless workflow for the preparation, purification and analysis of protein-DNA conjugates. proFIRE® is a unique system for protein-DNA conjugate preparation, delivering consistent and superior...
Read full Article Publication I March 18, 2020 An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2 The recognition of cis-regulatory RNA motifs in human transcripts by RNA binding proteins (RBPs) is essential...