Read full Article Brochure I May 2, 2017 Biophysical analysis of Cas9-DNA interactions and enzymatic activity with the switchSENSE® Biosensor Platform The analysis of the biophysical properties of Cas9 – DNA interactions (binding kinetics, affinity, endonuclease...
Read App Note App Note I April 8, 2017 Hydrodynamic diameter and thermal stability measurements of protein kinase A using switchSENSE® Protein kinases are enzymes that play a key role in cell regulation. One of the best understood kinases from a biochemical point of...
Read full Article Publication I April 15, 2017 switchSENSE: A new technology to study protein-RNA interactions. Characterization of RNA-binding protein interactions with RNA became inevitable to properly understand the cellular mechanisms involved in gene expression...
Read full Article Publication I February 17, 2017 Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon Bacteria can become transiently tolerant to several classes of antibiotics. This phenomenon known as persistence is regulated...
Read full Article Publication I February 2, 2017 The long zinc finger domain of PRDM9 forms a highly stable and long-lived complex with its DNA recognition sequence PR domain containing protein 9 (PRDM9) is a meiosis-specific, multi-domain protein that regulates the...
