What is a chip status test? How do I interpret the results?

A chip status test gives you important information about the quality of your chip. We recommend performing a chip status test before each assay. The chip test assay performs a regeneration step during which the surface is functionalized with blank Adapter strands, a...

How can I renew the chip surface for my next measurement?

To reuse your chip, you simply perform a chip functionalization. This includes two steps: a regeneration and the hybridization of new ligand strands. During the regeneration, all bound analytes and immobilized ligands are removed from the chip surface using the...

Can I work with complex sample media (cell lysates, serum, …)?

Generally, switchSENSE® can tolerate measurements in a variety of complex matrices, including cell lysates and high serum concentrations up to 80 %. Nevertheless, measurements in complex media usually require a certain degree of assay development. In most cases, this...

Can I measure the catalytic activity of enzymes?

Yes, you can. And there’s more to it than that. You can even differentiate between the association of DNA/RNA binding enzymes and their catalytic activity and independently examine the effects of inhibitors on these processes.