The heliX® device is equipped with two spots allowing for simultaneous measurements. One of the two spots may be used for the actual binding kinetics experiment (“measurement spot”) while the other one serves as a ligand-free reference (“reference spot”). In this...
The purpose of reference-correction, or referencing for short, is to extract the actual binding kinetics signals from the raw fluorescence signals measured by the heliX® device. Referencing aims to remove any artifacts / side effects such as signal drifts, signal...
The heliX+ instrument enables you to switch between different plate formats and sample vial volumes. You simply need to change the format in heliOS: click on the “sample tray” icon in your assay workflow and choose the format in the dropdown menu.
Generally, the software will notify you if your chip is not aligned correctly. The electrode images can additionally give you some information about the alignment. If each excitation light spot fully illuminates one of the two electrodes, the alignment is good. If a...
Yes, you can reuse the chip many times! The exact lifetime depends on your specific experimental conditions.
