Read full Article Publication I May 2, 2024 Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1 The optimization of the affinity of monoclonal antibodies is crucial for the development of drug candidates, as...
View Webinar Webinar I April 17, 2024 DISCOVER therapeutic antibodies: kinetics of antibody-drug conjugates measured directly on cells This is the third episode of our second season of the DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about...
View Webinar Webinar I March 18, 2024 DISCOVER protein-DNA conjugate purification: Effortless conjugate preparation, purification, and analysis with the proFIRE® This is the second episode of the second season of the DISCOVER MOLECULAR INTERACTIONS webinar series....
Read full Article Publication I January 18, 2024 DNA origami traps for large viruses Virus-enveloping macromolecular shells or tilings can prevent viruses from entering cells. Here, we describe the design and assembly of a cone-shaped DNA origami higher-order assembly...
Read full Article Publication I December 7, 2023 Kinetic FRET Assay to Measure Binding-Induced Conformational Changes of Nucleic Acids The interaction of small molecules or proteins with RNA or DNA often involves changes in the nucleic acid (NA) folding and structure....
