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Sensitive Protein Detection Using Site-Specifically Oligonucleotide-Conjugated Nanobodies

Read full Article Publication I July 5, 2022 Sensitive Protein Detection Using Site-Specifically Oligonucleotide-Conjugated Nanobodies High-quality affinity probes are critical for sensitive and specific protein detection, in particular for detection of protein...

DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease

Read full Article Publication I August, 2020 DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease Repair of covalent DNA-protein crosslinks (DPCs) by DNA-dependent proteases has emerged as an essential genome maintenance mechanism required...

A compact nanobody-DNAzyme conjugate enables antigen detection and signal amplification

Read full Article Publication I May, 2020 A compact nanobody-DNAzyme conjugate enables antigen detection and signal amplification Hemin-utilizing G-quadruplex DNAzymes with peroxidase-like (POX) activity are widely used as signal reporters in biosensing technology....

Preparation of single- and double-oligonucleotide antibody conjugates and their application for protein analytics

Read full Article Publication I January 29, 2020 Preparation of single- and double-oligonucleotide antibody conjugates and their application for protein analytics Oligonucleotide-conjugated antibodies have gained importance for their use in protein diagnostics. The...

Site-specific covalent conjugation and purification of His-tagged proteins to DNA for switchSENSE® applications I App Note

Read App Note App Note I January 9, 2020 Site-specific covalent conjugation and purification of His-tagged proteins to DNA for switchSENSE® applications In this application note, we introduce a conjugation kit for a straightforward, site-selective and covalent...
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