App Note I January 9, 2020

Site-specific covalent conjugation and purification of His-tagged proteins to DNA for switchSENSE® applications

In this application note, we introduce a conjugation kit for a straightforward, site-selective and covalent conjugation of His-tagged proteins to DNA with high efficiency using lower amounts of protein. Since they constitute one of the starting points for using the switchSENSE® technology, we developed this conjugation kit.