Read full Article Brochure I May 2, 2017 Biophysical analysis of Cas9-DNA interactions and enzymatic activity with the switchSENSE® Biosensor Platform The analysis of the biophysical properties of Cas9 – DNA interactions (binding kinetics, affinity, endonuclease...
Read full Article Publication I July 10, 2013 Protein analysis by time-resolved measurements with an electro-switchable DNA chip Measurements in stationary or mobile phases are fundamental principles in protein analysis. Although the immobilization of molecules on...
Read full Article Publication I July 15, 2015 Polymerase/DNA interactions and enzymatic activity: multiparameter analysis with electroswitchable biosurfaces The engineering of high-performance enzymes for future sequencing and PCR technologies as well as the...
Read App Note App Note I January 26, 2017 switchSENSE® for the characterization of polymerases switchSENSE® is the first and only chip-based biosensor that employs electro-switchable biosurfaces (ESB) for the biophysical analysis of molecular interactions. Two signals...
Read App Note App Note I December 22, 2016 Quantifying DNA exonuclease activity using a switchSENSE® hybridization assay The activity of the T5 exonuclease is quantified in a simple and quick workflow. This study demonstrates that the presence of T5 exonuclease down...