Read full Article Publication I April 28, 2022 Highly shape- and size-tunable membrane nanopores made with DNA Membrane nanopores are key for molecular transport in biology, portable DNA sequencing1,2,3,4, label-free single-molecule...
Read full Article Publication I April 28, 2022 Multivalent Binding Kinetics Resolved by Fluorescence Proximity Sensing Multivalent protein interactors are an attractive modality for probing protein function and exploring novel pharmaceutical strategies. The throughput...
watch tutorial Tutorial I May 18, 2022 Tight Binders Tutorial Affinity becomes challenging to measure for so-called “tight-binding” ligands that possess low dissociation rate constants (kD, or “off-rate” constant) where progress toward equilibrium is inversely...
Download Brochure Brochure I January 24, 2022 Molecular interactions with nucleic acidsStudying nucleic acid binding molecules with switchSENSE® Easy biosensor modification with specific nucleic acid sequences Real-time off-target binding information High...
Read full Article Publication I January 5, 2022 The role of DNA nanostructures in the catalytic properties of an allosterically regulated protease DNA-scaffolded enzymes typically show altered kinetic properties; however, the mechanism behind this phenomenon is still...
