Brochure I February 1, 2023

Real-Time Interaction Cytometry (RT-IC): Measure the binding of molecules to membrane targets on cells

This brochure explains how to characterize interactions involving antibodies, receptors, and membrane targets where they matter: in their native environments. RT-IC facilitates the automated analysis of kon and koff binding rates directly on cells.

It employs flow-permeable, biocompatible cell traps to physically retain single cells on the surface of the heliXcyto chip. Applications of RT-IC include the development of antibodies, CAR-T and other cell therapies, or tackling difficult targets like GPCRs.