Read full Article Publication I November 2020 Affinity of chlordecone and chlordecol for human aerum lipoproteins Chlordecone (CLD) is a chlorinated persistent organic pollutant (POP) whose presence despite the 1993 ban in agriculture areas has caused numerous public... Nucleotide binding kinetics and conformational change analysis of tissue transglutaminase with switchSENSE I Paper Function, activity, and interactions of proteins crucially depend on their three-dimensional structure and are often regulated by effector binding and... The trimer to monomer transition of Tumor Necrosis Factor-Alpha is a dynamic process that is significantly altered by therapeutic antibodies I Paper The cytokine tumor necrosis factor-alpha (TNF-α) readily forms homotrimers at sub-nM concentrations to promote... CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells I Paper Aminoacyl-tRNA synthetases (aaRSs) are ubiquitously expressed enzymes catalyzing the charging of tRNAs with their... A DNA-based biosensor assay for the kinetic characterization of ion-dependent aptamer folding and protein binding I Publication Therapeutic and diagnostic aptamers are nucleic acid oligomers designed to bind tightly and specifically to their target. Here, we present... 