View Webinar Webinar I April 17, 2024 DISCOVER small molecule-induced protein conformational changes using DNA origami nanolevers This is the sixth episode of our second season of the DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about...
Read full Article Publication I June 7, 2024 Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn Monoclonal antibodies (mAbs) as therapeutics necessitate favorable pharmacokinetic properties, including extended...
Read full Article Publication I May 2, 2024 Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1 The optimization of the affinity of monoclonal antibodies is crucial for the development of drug candidates, as...
View Webinar Webinar I October 16, 2023 DISCOVER protein conformational changes with electrically actuated DNA origami nanolevers. This is the sixth episode of our DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about cutting-edge drug...
Read full Article Publication I January 13, 2023 The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2 In addition to the classic functions of proteins, such as acting as a biocatalyst or binding partner, the conformational...
