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DISCOVER bispecific antibodies: generation, biophysical characterization and functional validation

View Webinar Webinar I November 13, 2024 DISCOVER bispecific antibodies: generation, biophysical characterization and functional validation This is the eighth episode of our second season of the DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk...

DISCOVER reverse transcriptase activity: catalytic rates of nucleic acid-modifying enzymes

View Webinar Webinar I September 17, 2024 DISCOVER reverse transcriptase activity: catalytic rates of nucleic acid-modifying enzymes This is the seventh episode of our second season of the DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about...

DISCOVER small molecule-induced protein conformational changes using DNA origami nanolevers

View Webinar Webinar I April 17, 2024 DISCOVER small molecule-induced protein conformational changes using DNA origami nanolevers This is the sixth episode of our second season of the DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about...

Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn

Read full Article Publication I June 7, 2024 Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn Monoclonal antibodies (mAbs) as therapeutics necessitate favorable pharmacokinetic properties, including extended...

Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1

Read full Article Publication I May 2, 2024 Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1 The optimization of the affinity of monoclonal antibodies is crucial for the development of drug candidates, as...
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