View Webinar Webinar I October 16, 2023 DISCOVER protein conformational changes with electrically actuated DNA origami nanolevers. This is the sixth episode of our DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about cutting-edge drug...
Read full Article Publication I January 13, 2023 The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2 In addition to the classic functions of proteins, such as acting as a biocatalyst or binding partner, the conformational...
Read More App Note switchSENSE® Compatibility Sheet The switchSENSE® compatibility provides an overview on different conditions switchSENSE® measurements can be performed in. ...
Read full Article Publication I June 18, 2021 Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action The receptor tyrosine kinase HER2 acts as oncogenic driver in numerous cancers. Usually, the gene is amplified, resulting in receptor...
Read full Article Publication I April 21, 2021 Biophysical Studies of the Binding of Viral RNA with the 80S Ribosome Using switchSENSE® Translation initiation, in both eukaryotes and bacteria, requires essential elements such as mRNA, ribosome , initiator tRNA, and...