Read App Note App Note I November 21, 2018 Measuring ligation activity of T4 DNA ligase on nicked DNA with switchSENSE® DNA ligases fulfill essential functions in DNA replication, DNA repair, and are standard tools in molecular biology labs. Here, we describe a...
Read App Note App Note I November 12, 2018 Sizing Analysis of the Ubiquitin / E1-E2-E3 Complex using switchSENSE® technology During the posttranslational process of ubiquitination, the small regulatory protein ubiquitin (Ub) is covalently attached to a lysine residue...
Read App Note App Note I March 3, 2018 High-affinity capturing of tagged proteins on the switchSENSE® biochip using Strep-Tactin®XT Antibody oligonucleotide conjugates are playing a significant role for a wide range of diagnostic and therapeutic applications....
Read App Note App Note I April 8, 2017 Hydrodynamic diameter and thermal stability measurements of protein kinase A using switchSENSE® Protein kinases are enzymes that play a key role in cell regulation. One of the best understood kinases from a biochemical point of...
Read App Note App Note I January 26, 2017 switchSENSE® for the characterization of polymerases switchSENSE® is the first and only chip-based biosensor that employs electro-switchable biosurfaces (ESB) for the biophysical analysis of molecular interactions. Two signals...