Read App Note App Note I January 9, 2020 Site-specific covalent conjugation and purification of His-tagged proteins to DNA for switchSENSE® applications In this application note, we introduce a conjugation kit for a straightforward, site-selective and covalent...
Read App Note App Note I February 8, 2019 A new biosensor-based assay for aptamer-protein interaction analysis Here we show how aptamer-protein interactions can be analyzed with DNA-based biosensors. To this end, we study the salt-dependence and sequence and structure...
Read App Note App Note I January 31, 2019 High-affinity capturing of antibodies on the switchSENSE® biochipusing CaptureSelect™ affinity ligands For biomolecular interaction analysis non-covalent ligand immobilization strategies are commonly used as they require no...
Read App Note App Note I January 7, 2019 Reverse Transcriptase binding and activity assays with switchSENSE® Reverse transcriptase (RT) is an enzyme found in retroviruses that catalyzes the conversion of single-stranded RNA into double-stranded cDNA. This function of...
Read App Note App Note I November 21, 2018 Measuring ligation activity of T4 DNA ligase on nicked DNA with switchSENSE® DNA ligases fulfill essential functions in DNA replication, DNA repair, and are standard tools in molecular biology labs. Here, we describe a...
