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Sinorhizobium meliloti YrbA binds divalent metal cations using two conserved histidines

Read full Article Publication I october 06, 2020 Sinorhizobium meliloti YrbA binds divalent metal cations using two conserved histidines Sinorhizobium meliloti is a nitrogen-fixing bacterium forming symbiotic nodules with the legume Medicago truncatula. S....

Nucleotide binding kinetics and conformational change analysis of tissue transglutaminase with switchSENSE

Read full Article Publication I September 15, 2020 Nucleotide binding kinetics and conformational change analysis of tissue transglutaminase with switchSENSE® Function, activity, and interactions of proteins crucially depend on their three-dimensional structure and...

The trimer to monomer transition of Tumor Necrosis Factor-Alpha is a dynamic process that is significantly altered by therapeutic antibodies

Read full Article Publication I June 09, 2020 The trimer to monomer transition of Tumor Necrosis Factor-Alpha is a dynamic process that is significantly altered by therapeutic antibodies The cytokine tumor necrosis factor-alpha (TNF-α) readily forms homotrimers at...

DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease

Read full Article Publication I August, 2020 DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease Repair of covalent DNA-protein crosslinks (DPCs) by DNA-dependent proteases has emerged as an essential genome maintenance mechanism required...

Molecular Dynamics to Elucidate the DNA-Binding Activity of AlpZ, a Member of the Gamma-Butyrolactone Receptor Family in Streptomyces ambofaciens

Read full Article Publication I July 2, 2020 Molecular Dynamics to Elucidate the DNA-Binding Activity of AlpZ, a Member of the Gamma-Butyrolactone Receptor Family in Streptomyces ambofaciens Signaling molecule receptors play a central role in quorum sensing and in the...
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