Read full Article Publication I November 6, 2019 Validation of the Slow Off-Kinetics of Sirtuin-Rearranging Ligands (SirReals) by Means of Label-Free Electrically Switchable Nanolever Technology We have discovered the sirtuin‐rearranging ligands (SirReals) to be...
Read full Article Publication I March 11, 2020 Resolving Binding Events on the Multifunctional Human Serum Albumin Physiological processes rely on initial recognition events between cellular components and other molecules or modalities. Biomolecules can have multiple...
Read App Note App Note I January 9, 2020 Site-specific covalent conjugation and purification of His-tagged proteins to DNA for switchSENSE® applications In this application note, we introduce a conjugation kit for a straightforward, site-selective and covalent...
Read full Article Publication I September 9, 2019 CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells Aminoacyl-transfer RNA (tRNA) synthetases (aaRSs) are the largest protein...
Read full Article Publication I August 8, 2019 A DNA-based biosensor assay for the kinetic characterization of ion-dependent aptamer folding and protein binding Therapeutic and diagnostic aptamers are nucleic acid oligomers designed to bind tightly and specifically...
