Chip regeneration implies that all ligand molecules immobilized on switchSENSE® electrodes in one flow channel and all potentially bound analyte molecules are completely washed off the sensor surfaces by treatment with a regeneration solution. This leaves...
The Dynamic Response (DR) is a parameter that characterizes the switching speed of DNA nanolevers. It is automatically calculated from the raw data by the switchSENSE® software package. For every recorded data point, the software evaluates typically the upward motion...
The hydrodynamic diameter (Dh) of a molecule is defined as the diameter of a perfect solid sphere that would exhibit the same hydrodynamic friction as the molecule of interest. Thus, the Dh value reflects primarily the hydrodynamic friction but is usually also a good...
The Lollipop model is a biophysical model used in DRX instruments to provide an estimated size of the protein of interest in form of the hydrodynamic diameter. The model assumes that the DNA nanolevers are a charged and rigid cylinder and the attached protein...
Please see section “What are the signals that can be derived from switchSENSE® experiments?”.
