Molecular Dynamics Hydrodynamic changes can be detected as changes in the Dynamic Response. Generally, events that increase the hydrodynamic friction, such as binding of an analyte molecule to the ligand, result in a slower switching motion, which can be observed as a...
switchSENSE® is a biophysical research technology to investigate molecular interactions. The core of this technology are DNA nanolevers attached to gold microelectrodes. These DNA nanolevers can easily be customized with any ligand of choice. The orientation of the...
For biophysical experiments, a switchSENSE® measurement combines two aspects: A fluorescence measurement, where the fluorophore emission intensity is subject to two influences: a non-radiative energy transfer to the metal electrode, which depends on the distance...
The easiest way to check if your flow channel is suitable for the planned experiment, is to perform a status check of the desired flow channel. For further reading please see “What is a chip status test and how should I interpret it?”.
