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Kinetics of multispecific molecules: Analysis of cooperative binding with switchSENSE®

Download Brochure Brochure I October 20, 2021 Kinetics of multispecific binders:Analysis of cooperative binding with switchSENSE® switchSENSE® FEATURES: Straightforward sensor functionalization with two different antigens. Variable ligand density to control...

Tailored Biosensors for Drug Screening, Efficacy Assessment, and Toxicity Evaluation

Read full Article Publication I September 13, 2021 Tailored Biosensors for Drug Screening, Efficacy Assessment, and Toxicity Evaluation Biosensors have been flourishing in the field of drug discovery with pronounced developments in the past few years. They facilitate...

Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion

Read full Article Publication I September 07, 2021 Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion Many cadherin family proteins are associated with diseases such as cancer. Since cell adhesion requires homodimerization...

Electrically Switchable Nanolever Technology for the Screening of Metal-Chelating Peptides in Hydrolysates

Read full Article Publication I April 28, 2022 Electrically Switchable Nanolever Technology for the Screening of Metal-Chelating Peptides in Hydrolysates Metal-chelating peptides (MCP) are considered as indirect antioxidants due to their capacity to inhibit radical...

Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action

Read full Article Publication I June 18, 2021 Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action The receptor tyrosine kinase HER2 acts as oncogenic driver in numerous cancers. Usually, the gene is amplified, resulting in receptor...
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