Brochure I October 20, 2021
Kinetics of multispecific binders:
Analysis of cooperative binding with switchSENSE®
Straightforward sensor functionalization with two different antigens.
Variable ligand density to control interlinking when multivalent binders are measured.
Easily adjustable antigen surface ratios to mimic cell surface abundances.
Two-color detection to monitor each interaction individually.
Stable signals for long dissociations to measure slow avidity off-rates.
heliOS software with multi-phasic fitting algorithms to differentiate affinity from avidity.