App Note I May 17, 2017 List of protein hydrodynamic diameters DH ProteinMolecular weightDH measured with switchSENSE® (i)Dh calculated from PDB file (ii)PDB codeStructure anti-human Fab fragment050 kDa06.6 nm07.2 nm3WD5 anti-human IgG150 kDa12.7 nm11.2 nm1IGT...
Read App Note App Note I January 17, 2016 Real-time measurements of DNA exonucleases The activities of the 5’→3’ exonucleases T5 exonuclease and Lambda exonuclease could be analyzed using a switchSENSE molecular ruler assay. The assay can be applied for evaluating...
Read App Note App Note I July 13, 2015 Characterization of a high-affinity anti-EPO antibody by switching speed measurements Erythropoietin (EPO) is a glycoprotein that upregulates the production of red blood cells. Recombinantly produced EPO is used as a drug to...
Read App Note App Note I January 15, 2014 Inhibitor induced shifts in the thermal stability of carbonic anhydrase The thermal stability of proteins can be investigated by measuring the switching dynamics of proteinnanolever conjugates as a function of temperature....
Read full Article Publication I November 20, 2012 Messung molekularer Interaktion mit dynamischen Oberflächensensoren A novel label-free biosensing technology is introduced which employs a dynamically switchable biosurface. Contrary to conventional biosensors,...
