switchSENSE®
Application
Library

Inhibitor induced shifts in the thermal stability of carbonic anhydrase I App Note

The thermal stability of proteins can be investigated by measuring the switching dynamics of proteinnanolever conjugates as a function of temperature. Here, we determine the melting temperature TM of human carbonic anhydrase 1 (hCA1) with switchSENSE® and examine the influence of different inhibitors with pharmaceutical relevance on the thermal denaturation of hCA1.

Download PDF Document

Authors: Thomas Welte, Ulrich Rant (January 2014)

CONTACT US!
WE WILL GET IN TOUCH WITH YOU SHORTLY.

What are you interested in? *

Consumables & Reagents
Technical Support
Quotes & Orders

Instruments & Applications
Technical & Software Support
Assay Development

New to switchSENSE®
General Info & Evaluation
Purchasing

    Dynamic Biosensors Data Privacy Policy

    Contact Specialist