Read More App Note Biophysical Analysis of CRBN Variants in PROTAC Ternary Kinetics Proteolysis-targeting chimeras (PROTACs) and molecular glues have emerged as powerful therapeutic modalities by exploiting the ubiquitin–proteasome system to drive selective protein...
Download Brochure Brochure I November 29, 2024 single-cell Interaction Cytometry (scIC): Measure the binding of molecules to membrane targets on cells This brochure explains how to characterize interactions involving antibodies, receptors, and membrane targets where...
Read full Article Publication I June 7, 2024 Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn Monoclonal antibodies (mAbs) as therapeutics necessitate favorable pharmacokinetic properties, including extended...
View Webinar Webinar I May 14, 2024 DISCOVER screening of PROTACs/molecular glues: ternary complex analysis with induced proximity This is the fourth episode of our second season of the DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about...
Read More App Note Real-time measurement of DNA polymerase activity and inhibition with switchSENSE® and the heliX® biosensor Polymerases play a key role in all living cells for the replication and preservation of genetic information. They are also interesting drug...
