smart
biophysical
analysis

switchSENSE® Technology
Molecular Interaction Analysis
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  • Binding Kinetics
  • Binding Affinity
  • Protein Diameter
  • Conformation Changes
  • Nuclease & Polymerase Activities
  • Bispecific Binders & Avidity
  • Melting & Thermodynamics
  • Aggregation

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Drug Development for Biologics and Small Molecules

Fresh information, earlier in the pipeline switchSENSE® identifies and thoroughly characterizes potential hits through advanced kinetics and biophysical characterization of size, shape and conformation.

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Quality Control in Production Process Monitoring

Characterizing enzyme activity and reproducible lot-by-lot quality measurements, switchSENSE® offers a brand new tool – extremely rapid, highly insightful, radiation free.

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Biophysical Analysis in Life Science Research

In tandem with our high specificity kinetic measurements, switchSENSE® uses molecular rulers and the measurement of molecular dynamics to give real time mapping of size, conformation, shape and position of interacting partners.

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In Focus

Research

We are working on

CRISPR / Cas9

You, too?

Let`s talk, contact us!

Products for High-Performance Analysis

Biochips

switchSENSE® experiments are performed on a multi-electrode biochip arranged in 4 separate flow channels.

DRX Instruments

Our switchSENSE® instruments are the first systems to measure the motion of biomolecules on a chip.

Consumables

All the necessary coupling, demo & OQ kits, starter kits & other consumables you may need for your switchSENSE® studies.

User statements

Dr. Michael Schraeml, Head Protein and Enzyme Technologies
ROCHE DIAGNOSTICS GMBH