Read full Article Publication I July 5, 2022 Sensitive Protein Detection Using Site-Specifically Oligonucleotide-Conjugated Nanobodies High-quality affinity probes are critical for sensitive and specific protein detection, in particular for detection of protein...
Read full Article Publication I June 19, 2022 A Robust Assay to Monitor Ataxin-3 Amyloid Fibril Assembly Spinocerebellar ataxia type 3 (SCA3) is caused by the expansion of a glutamine repeat in the protein ataxin-3, which is deposited as intracellular aggregates in...
Read full Article Publication I April 28, 2022 Highly shape- and size-tunable membrane nanopores made with DNA Membrane nanopores are key for molecular transport in biology, portable DNA sequencing1,2,3,4, label-free single-molecule...
Read full Article Publication I April 28, 2022 Multivalent Binding Kinetics Resolved by Fluorescence Proximity Sensing Multivalent protein interactors are an attractive modality for probing protein function and exploring novel pharmaceutical strategies. The throughput...
Read full Article Publication I January 5, 2022 The role of DNA nanostructures in the catalytic properties of an allosterically regulated protease DNA-scaffolded enzymes typically show altered kinetic properties; however, the mechanism behind this phenomenon is still...
