Read full Article Publication I December 7, 2023 Kinetic FRET Assay to Measure Binding-Induced Conformational Changes of Nucleic Acids The interaction of small molecules or proteins with RNA or DNA often involves changes in the nucleic acid (NA) folding and structure....
Read full Article Publication I November 27, 2023 Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction The classical Non-Homologous End Joining (c-NHEJ) pathway is the predominant process in mammals...
View Webinar Webinar I May 11, 2023 DISCOVER small molecule induced aptamer folding: a biosensor assay to detect structural changes. This is the second episode of our DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about cutting-edge drug...
Read full Article Publication I January 13, 2023 The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2 In addition to the classic functions of proteins, such as acting as a biocatalyst or binding partner, the conformational...
Read More App Note switchSENSE® Compatibility Sheet The switchSENSE® compatibility provides an overview on different conditions switchSENSE® measurements can be performed in. ...